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Bujnicki Lab Homepage

ruvA

Unnamed Gene ID: 946369

Known also as: ECK1862; JW1850;


NCBI Gene ID: 946369
Species: Escherichia coli strain K-12 substr. MG1655

Binds Holliday junction as two tetramers (an octamer) and each tetrameric half recruits one RuvB hexameric helicase. [More information is available at EcoGene: EG10923]. RuvABC is an enzymatic complex which functions in recombination pathways to by binding to recombinational junctions and catalyzing strand cleavage and branch migration. [More information is available at EcoCyc: RUVA].


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Benson F, Collier S, Lloyd RG Evidence of abortive recombination in ruv mutants of Escherichia coli K12. Mol Gen Genet Jan. 1, 1991
Takahagi M, Iwasaki H, Nakata A, Shinagawa H Molecular analysis of the Escherichia coli ruvC gene, which encodes a Holliday junction-specific endonuclease. J Bacteriol Sept. 1, 1991
Taylor AF Movement and resolution of Holliday junctions by enzymes from E. coli. Cell June 26, 1992
Tsaneva IR, Muller B, West SC ATP-dependent branch migration of Holliday junctions promoted by the RuvA and RuvB proteins of E. coli. Cell June 26, 1992
Tsaneva IR, Illing G, Lloyd RG, West SC Purification and properties of the RuvA and RuvB proteins of Escherichia coli. Mol Gen Genet Oct. 1, 1992

Last modification of this entry: Oct. 6, 2010.

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