REPAIRtoire - a database of DNA repair pathways

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Bujnicki Lab Homepage

mutL

Unnamed Gene ID: 948691

Known also as: ECK4166; JW4128;


NCBI Gene ID: 948691
Species: Escherichia coli strain K-12 substr. MG1655

MutL DNA-binding is required for methyl-directed mismatch repair (Robertson, 2006). [More information is available at EcoGene: EG11281]. MutL is one of the components of the MutHLS complex. [More information is available at EcoCyc: EG11281].


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Cox EC, Gibson TC Selection for high mutation rates in chemostats. Genetics June 1, 1974
Rayssiguier C, Thaler DS, Radman M The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants. Nature Nov. 23, 1989
Connolly DM, Winkler ME Structure of Escherichia coli K-12 miaA and characterization of the mutator phenotype caused by miaA insertion mutations. J Bacteriol March 1, 1991
Bende SM, Grafstrom RH The DNA binding properties of the MutL protein isolated from Escherichia coli. Nucleic Acids Res April 11, 1991
Tsui HT, Mandavilli BS, Winkler ME Nonconserved segment of the MutL protein from Escherichia coli K-12 and Salmonella typhimurium. Nucleic Acids Res May 11, 1992

Last modification of this entry: Oct. 6, 2010.

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