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phr
Unnamed Gene ID: 947005
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Known also as: ECK0697; JW0698; phrB;
The flavoprotein DNA photolyase uses light to repair cyclobutylpyrimidine dimers in DNA. [More information is available at EcoGene: EG10736]. Exposing Escherichia coli to UV radiation at wavelengths near the absorption maximum of DNA produces cyclobutane-type pyrimidine dimers (CPDs) as well as, to a lesser degree, 6-4 pyrimidine-pyrimidones in its DNA. [More information is available at EcoCyc: EG10736].
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Gene sequence:
Proteins coded by this gene:
References:
Authors
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Title
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Journal
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Sancar GB, Smith FW, Sancar A
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Identification and amplification of the E. coli phr gene product.
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Nucleic Acids Res
Oct. 11, 1983
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Husain I, Sancar A
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Photoreactivation in phr mutants of Escherichia coli K-12.
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J Bacteriol
June 1, 1987
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Li YF, Sancar A
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Active site of Escherichia coli DNA photolyase: mutations at Trp277 alter the selectivity of the enzyme without affecting the quantum yield of photorepair.
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Biochemistry
June 19, 1990
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Lorence MC, Maika SD, Rupert CS
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Physical analysis of phr gene transcription in Escherichia coli K-12.
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J Bacteriol
Nov. 1, 1990
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Yamamoto K
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Dissection of functional domains in Escherichia coli DNA photolyase by linker-insertion mutagenesis.
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Mol Gen Genet
March 1, 1992
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Last modification of this entry: Oct. 6, 2010.
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