REPAIRtoire - a database of DNA repair pathways

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Bujnicki Lab Homepage

RAD50

Unnamed Gene ID: 855471


NCBI Gene ID: 855471
Species: Saccharomyces cerevisiae

Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Gorbalenya AE, Koonin EV Superfamily of UvrA-related NTP-binding proteins. Implications for rational classification of recombination/repair systems. J Mol Biol June 20, 1990
Chen L, Trujillo KM, Van Komen S, Roh DH, Krejci L, Lewis LK, Resnick MA, Sung P, Tomkinson AE Effect of amino acid substitutions in the rad50 ATP binding domain on DNA double strand break repair in yeast. J Biol Chem Feb. 28, 2005
Bhaskara V, Dupre A, Lengsfeld B, Hopkins BB, Chan A, Lee JH, Zhang X, Gautier J, Zakian V, Paull TT Rad50 adenylate kinase activity regulates DNA tethering by Mre11/Rad50 complexes. Mol Cell March 9, 2007
Ghosal G, Muniyappa K The characterization of Saccharomyces cerevisiae Mre11/Rad50/Xrs2 complex reveals that Rad50 negatively regulates Mre11 endonucleolytic but not the exonucleolytic activity. J Mol Biol Sept. 28, 2007

Last modification of this entry: Oct. 6, 2010.

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