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mutY
Unnamed Gene ID: 947447
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Known also as: ECK2956; JW2928; micA; mutB;
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MutY serves as an adenine glycosylase mismatch repair enzyme in Escherichia coli which works to correct G-A mispairs to G-C base pairs. [More information is available at EcoCyc: EG10627].
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Gene sequence:
Proteins coded by this gene:
References:
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Authors
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Title
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Journal
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Cox EC, Gibson TC
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Selection for high mutation rates in chemostats.
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Genetics
June 1, 1974
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Nghiem Y, Cabrera M, Cupples CG, Miller JH
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The mutY gene: a mutator locus in Escherichia coli that generates G.C----T.A transversions.
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Proc Natl Acad Sci U S A
April 1, 1988
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Michaels ML, Pham L, Nghiem Y, Cruz C, Miller JH
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MutY, an adenine glycosylase active on G-A mispairs, has homology to endonuclease III.
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Nucleic Acids Res
July 11, 1990
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Tsai-Wu JJ, Radicella JP, Lu AL
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Nucleotide sequence of the Escherichia coli micA gene required for A/G-specific mismatch repair: identity of micA and mutY.
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J Bacteriol
March 1, 1991
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Tsai-Wu JJ, Liu HF, Lu AL
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Escherichia coli MutY protein has both N-glycosylase and apurinic/apyrimidinic endonuclease activities on A.C and A.G mispairs.
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Proc Natl Acad Sci U S A
Sept. 15, 1992
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Last modification of this entry: Oct. 6, 2010.
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