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nth
Unnamed Gene ID: 947122
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Known also as: ECK1629; JW1625;
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Nth is specific for damaged pyrimidine sites, particularly Thy. [More information is available at EcoGene: EG10662]. Endonuclease III or Nth is a DNA glycosylase that recognizes pyrimidine residues damaged by ring saturation, ring fragmentation or ring contraction. [More information is available at EcoCyc: EG10662].
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Gene sequence:
Proteins coded by this gene:
References:
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Authors
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Title
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Journal
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Cunningham RP, Weiss B
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Endonuclease III (nth) mutants of Escherichia coli.
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Proc Natl Acad Sci U S A
Feb. 1, 1985
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Weiss B, Cunningham RP
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Genetic mapping of nth, a gene affecting endonuclease III (thymine glycol-DNA glycosylase) in Escherichia coli K-12.
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J Bacteriol
May 1, 1985
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Bailly V, Verly WG
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Escherichia coli endonuclease III is not an endonuclease but a beta-elimination catalyst.
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Biochem J
March 1, 1987
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Kuo CF, McRee DE, Fisher CL, O'Handley SF, Cunningham RP, Tainer JA
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Atomic structure of the DNA repair [4Fe-4S] enzyme endonuclease III.
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Science
Oct. 16, 1992
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Thayer MM, Ahern H, Xing D, Cunningham RP, Tainer JA
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Novel DNA binding motifs in the DNA repair enzyme endonuclease III crystal structure.
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EMBO J
Aug. 15, 1995
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Last modification of this entry: Oct. 6, 2010.
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