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Heteroduplex DNA with single strand protected by RPA (3' directed)
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| Reaction | Previous state | Following state |
| RPA protects single stranded DNA (3' directed) in Saccharomyces cerevisiae | Heteroduplex DNA with nick 3' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex and ExoI, with partially excised errorenous strand in Saccharomyces cerevisiae | Heteroduplex DNA with single strand protected by RPA (3' directed) in Saccharomyces cerevisiae |
| Reaction | Previous state | Following state |
| ExoI excises erroneous strand some distance beyond the mismatch (3' directed) in Saccharomyces cerevisiae | Heteroduplex DNA with single strand protected by RPA (3' directed) in Saccharomyces cerevisiae | Heteroduplex DNA with removed mismatch (3' directed MMR) in Saccharomyces cerevisiae |
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