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NHEJ: Non-ligatable DNA ends are processed
[Homo sapiens]
| They may be processed in two ways - the 'classical' and DSB subset processing. The 'classical' one can be done either by resection of single-strand overhangs by Artemis, or by filling by polymerase. The DSB subset processing takes place when overhangs are partially complementary, and requires the XLF/Cernunnos complex. |
This is the reaction from:
 | DNA-PKcs autophosphorylated in Homo sapiens |
| to | |
 | processed non-ligatable ends in Homo sapiens |
References:
| Authors | Title | Journal |
| Weterings E, Chen DJ | The endless tale of non-homologous end-joining | Cell Res. Jan. 1, 2008 |
Keywords:
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