Welcome! Click here to login or here to register.
 |
|||||||||||||||||||
|
|||||||||||||||||||
 |
|||||||||||||||||||
thymidine glycol(5,6-dihydroxy-5,6-dihydrothymidine-5'-monophosphate) |
|
Smiles represantation:
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])OP(O)(O)=O)N1C(=O)N([H])C(=O)[C@@](O[H])(C([H])([H])[H])[C@@]1([H])O[H]
| One of the principal DNA lesions induced by oxidation and ionizing radiation, has been investigated in Escherichia coli. Thymine glycol was positioned at a unique site in the single-stranded genome of a bacteriophage M13mp19 derivative. Replication of the genome in E. coli yielded targeted mutations at a frequency of 0.3%; the mutations were exclusively T to C transitions. |
Download [.mol file for thymidine glycol] |
Sources:
Recognizing proteins:
| Protein | Species |
| NEIL1 | Homo sapiens |
| NEIL2 | Homo sapiens |
| NTH | Homo sapiens |
| Ntg1p | Saccharomyces cerevisiae |
| Nth | Escherichia coli |
Keywords:
Last modification of this entry: Oct. 16, 2010.
Add your own comment!
There is no comment yet.
|
|
|
|