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"The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro." |
Prelich G, Kostura M, Marshak DR, Mathews MB, Stillman B |
Published Jan. 1, 1987 in Nature volume 326 .
Pubmed ID: 2882422
Abstract:
| Cell-free extracts prepared from human 293 cells, supplemented with purified SV40 large-T antigen, support replication of plasmids containing the SV40 origin of DNA replication. A cellular protein (Mr approximately 36,000) that is required for efficient SV40 DNA synthesis in vitro has been purified from these extracts. This protein is recognized by human autoantibodies and is identified as the cell-cycle regulated protein known as proliferating cell nuclear antigen (PCNA) or cyclin. |
This publication refers to following REPAIRtoire entries:
| Proteins |
Last modification of this entry: Oct. 6, 2010
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