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"Cloning and characterization of the human RNA polymerase I subunit hRPA40."

Dammann R, Pfeifer GP



Published March 9, 1998 in Biochim Biophys Acta volume 1396 .

Pubmed ID: 9540830

Abstract:
The cloning of the human RNA polymerase I 40 kDa subunit, and the comparison of its amino acid sequence to other related RNA polymerase subunits are described. The amino acid sequence of hRPA40 has high homology to the mouse RNA polymerase I 40 kDa subunit (93%), to two Arabidopsis thaliana subunits (47%), the yeast RPC40 subunit (46%) and the human RNA polymerase II hRPB33 subunit (40%). Southern blot analysis shows that this gene is single copy and Northern blot analysis indicates that the mRNA of 1.3 kb is expressed in different cell types.


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Last modification of this entry: Oct. 6, 2010

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