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"MCM4 and PRKDC, human genes encoding proteins MCM4 and DNA-PKcs, are close neighbours located on chromosome 8q12-->q13." |
Ladenburger EM, Fackelmayer FO, Hameister H, Knippers R |
Published Jan. 1, 1997 in Cytogenet Cell Genet volume 77 .
Pubmed ID: 9284934
Abstract:
| A human genomic DNA fragment containing the 5' region of MCM4, a gene encoding replication protein MCM4/Cdc21 was isolated. At a distance of about 800 base pairs upstream of MCM4, the fragment was shown to also contain the 5' end of PRKDC, a gene encoding the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs). The genomic DNA fragment was used for hybridization to human metaphase chromosome spreads. The cytogenetic map location of the two closely adjacent genes was determined to be 8q12-->q13. |
This publication refers to following REPAIRtoire entries:
| Proteins |
Last modification of this entry: Oct. 6, 2010
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