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"Interaction of human recombination proteins Rad51 and Rad54."

Golub EI, Kovalenko OV, Gupta RC, Ward DC, Radding CM



Published Oct. 15, 1997 in Nucleic Acids Res volume 25 .

Pubmed ID: 9321665

Abstract:
The cDNA for human protein HsRad54, which is a structural homolog of Saccharomyces cerevisiae recombination/repair protein Rad54, was cloned and expressed in Escherichia coli. As demonstrated by analysis in vitro and in vivo, HsRad54 protein interacts with human Rad51 recombinase. The interaction is mediated by the N-terminal domain of HsRad54 protein, which interacts with both free and DNA-bound HsRad51 protein.


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Last modification of this entry: Oct. 6, 2010

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