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"The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme."

Jentsch S, McGrath JP, Varshavsky A



Published Jan. 1, 1987 in Nature volume 329 .

Pubmed ID: 3306404

Abstract:
The RAD6 gene of the yeast Saccharomyces cerevisiae is required for a variety of cellular functions including DNA repair. The discovery that the RAD6 gene product can catalyse the covalent attachment of ubiquitin to other proteins suggests that the multiple functions of the RAD6 protein are mediated by its ubiquitin-conjugating activity.


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Last modification of this entry: Oct. 6, 2010

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