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"Human TP53 from the malignant glioma-derived cell lines M059J and M059K has a cancer-associated mutation in exon 8." |
Anderson CW, Allalunis-Turner MJ |
Published Oct. 1, 2000 in Radiat Res volume 154 .
Pubmed ID: 11023613
Abstract:
| The protein coding segment of the TP53 genes from the glioma-derived cell lines M059J and M059K was sequenced. The sequences from both cell lines were identical over 5039 bp, including the gene segment containing exons 2 through 9, exon 10, and the proximal segment of exon 11. In both cells, the first nucleotide of codon 286 (GAA, Glu) is changed to an A (AAA, Lys). Comparison with the same TP53 segment from the A549 human lung carcinoma cell line revealed several differences in intron sequence. |
This publication refers to following REPAIRtoire entries:
| Proteins |
Last modification of this entry: Oct. 6, 2010
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