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"Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population."

Olschwang S, Laurent-Puig P, Vassal A, Salmon RJ, Thomas G



Published Jan. 1, 1991 in Hum Genet volume 86 .

Pubmed ID: 1999338

Abstract:
We describe a simple method for characterizing a frequent polymorphism (that substitutes an arginine for a proline) in the coding sequence of the Tp53 gene in patients with colonic cancer and in a control population. We could find no evidence that this polymorphism is associated with a marked predisposition to colorectal cancer.


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Last modification of this entry: Oct. 6, 2010

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