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"The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants." |
Rayssiguier C, Thaler DS, Radman M |
Published Nov. 23, 1989 in Nature volume 342 .
Pubmed ID: 2555716
Abstract:
| The requirement for DNA sequence homology in generalized genetic recombination is greatly relaxed in bacterial mutL, mutS and mutH mutants deficient in mismatch repair. In such mutants, intergeneric recombination occurs efficiently between Escherichia coli and Salmonella typhimurium, which are approximately 20% divergent in DNA sequence. This finding has implications for speciation, for regulating recombination between diverged repeated sequences, and for hitherto difficult interspecies hybridizations. |
This publication refers to following REPAIRtoire entries:
| Genes |
Last modification of this entry: Oct. 6, 2010
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