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"Escherichia coli xth mutants are hypersensitive to hydrogen peroxide."

Demple B, Halbrook J, Linn S



Published Jan. 1, 1983 in J Bacteriol volume 153 .

Pubmed ID: 6337115

Abstract:
Escherichia coli mutants lacking exonuclease III (xthA) are exceptionally sensitive to hydrogen peroxide. They are killed by H2O2 at 20 times the rate of wild-type bacteria and at 3 to 4 times the rate of recA cells. This is the first clear phenotypic sensitivity reported for xth- E. coli and should aid in clarifying peroxide-induced lethality and the in vivo role of exonuclease III.


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Last modification of this entry: Oct. 6, 2010

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