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Protein FULL name: MutS [Escherichia coli].
MutS (Escherichia coli strain K-12 substr. MG1655) is product of expression of
mutS
gene.
FUNCTION: This protein is involved in the repair of mismatches in
DNA. It is possible that it carries out the mismatch recognition
step. This protein has a weak ATPase activity.
INTERACTION:
P0A6N1:tufA; NbExp=1; IntAct=EBI-554920, EBI-301077;
SIMILARITY: Belongs to the DNA mismatch repair mutS family.
Links to other databases:
Protein sequence:
SAIENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLL
DISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPAT
SKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDIS
SGRFRLSEPADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPL
WEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTT
LPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTP
MGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTAGLQPVLRQVGDLERI
LARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEFA
ELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLE
VRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERY
IIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAE
LDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPL
NLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYVPAQKVEIGPID
RIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTST
YDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVHLDALE
HGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESISP
NAAATQVDGTQMSLLSVPE
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MutS (Escherichia coli strain K-12 substr. MG1655) is able to recognize following damages:
References:
Title
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Authors
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Journal
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The Escherichia coli fdv gene probably encodes mutS and is located at minute 58.8 adjacent to the hyc-hyp gene cluster.
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Schlensog V, Bock A
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J Bacteriol
Dec. 1, 1991
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The complete genome sequence of Escherichia coli K-12.
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Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y
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Science
Sept. 5, 1997
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Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
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Hayashi K, Morooka N, Yamamoto Y, Fujita K, Isono K, Choi S, Ohtsubo E, Baba T, Wanner BL, Mori H, Horiuchi T
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Mol Syst Biol
Jan. 1, 2006
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Last modification of this entry: Oct. 6, 2010.
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