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PolII |
Protein FULL name:
DNA polymerase II [Escherichia coli].
PolII (Escherichia coli strain K-12 substr. MG1655) is product of expression of polB gene.
PolII is involved in:
TLS in Escherichia coli strain K-12 substr. MG1655
Keywords:
FUNCTION: Thought to be involved in DNA repair and/or mutagenesis.
CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
ENZYME REGULATION: DNA polymerase II activity is regulated by the lexA gene during the SOS response.
INTERACTION: P0AC41:sdhA; NbExp=1; IntAct=EBI-1113379, EBI-371263;
SIMILARITY: Belongs to the DNA polymerase type-B family.
| NCBI GenPept GI number(s): |
147318 |
| Species: | Escherichia coli |
Links to other databases:
| Database | ID | Link |
| Uniprot | P21189 |
P21189 |
| PFAM: | - |
P21189 (Link - using uniprot id) |
| InterPro: | - |
P21189 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQV PRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGG VTVYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPL KWVSIDIETTRHGELYCIGLEACGQRIVYMLGPENGDASSLDFELEYVAS RPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERYRLPLRLGRDN SELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQEL LGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLKDCELVTQIFHKTEIMP FLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASP GGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFY GVLGTTACRFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTF VWLKGAHSEEEAAKIGRALVQHVNAWWAETLQKQRLTSALELEYETHFCR FLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTDWTPLAQQFQQ ELYLRIFRNEPYQEYVRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVP PHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTTGPEPPGLPTFTTGLR TLSDPPATTRGGGNTPFY |
PolII (Escherichia coli strain K-12 substr. MG1655) is able to recognize following damages:
PolII (Escherichia coli strain K-12 substr. MG1655) belongs to following protein families:
References:
| Title | Authors | Journal |
| DNA polymerase II is encoded by the DNA damage-inducible dinA gene of Escherichia coli. | Bonner CA, Hays S, McEntee K, Goodman MF | Proc Natl Acad Sci U S A Oct. 1, 1990 |
| Nucleotide sequence and deletion analysis of the polB gene of Escherichia coli. | Chen H, Sun Y, Stark T, Beattie W, Moses RE | DNA Cell Biol Nov. 1, 1990 |
| Escherichia coli DNA polymerase II is homologous to alpha-like DNA polymerases. | Iwasaki H, Ishino Y, Toh H, Nakata A, Shinagawa H | Mol Gen Genet April 1, 1991 |
| Systematic sequencing of the Escherichia coli genome: analysis of the 0-2.4 min region. | Yura T, Mori H, Nagai H, Nagata T, Ishihama A, Fujita N, Isono K, Mizobuchi K, Nakata A | Nucleic Acids Res July 11, 1992 |
| The Escherichia coli polB locus is identical to dinA, the structural gene for DNA polymerase II. Characterization of Pol II purified from a polB mutant. | Qiu Z, Goodman MF | J Biol Chem March 28, 1997 |
| The complete genome sequence of Escherichia coli K-12. | Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y | Science Sept. 5, 1997 |
| Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. | Hayashi K, Morooka N, Yamamoto Y, Fujita K, Isono K, Choi S, Ohtsubo E, Baba T, Wanner BL, Mori H, Horiuchi T | Mol Syst Biol Jan. 1, 2006 |
Last modification of this entry: July 7, 2011.
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