REPAIRtoire - a database of DNA repair pathways

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Bujnicki Lab Homepage

Ercc1

Protein FULL name:

DNA excision repair protein ERCC-1 isoform a [Mus musculus].


Ercc1 (Mus musculus) is product of expression of Ercc1 gene.






FUNCTION: Structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair.

SUBUNIT: Heterodimer composed of ERCC1 and XPF/ERRC4.

SUBCELLULAR LOCATION: Nucleus.

SIMILARITY: Belongs to the ERCC1/RAD10/SWI10 family.


NCBI GenPept GI number(s): 187960064
Species: Mus musculus

Links to other databases:

Database ID Link
Uniprot P07903 P07903
PFAM: - P07903 (Link - using uniprot id)
InterPro: - P07903 (Link - using uniprot id)
CATH: - -
SCOP: - -
PDB: - -


Protein sequence:
MDPGKDEESRPQPSGPPTRRKFVIPLEEEEVPCAGVKPLFRSSRNPTIPA
TSAHVAPQTYAEYAITQPPGGAGATVPTGSEPAAGENPSQTLKTGAKSNS
IIVSPRQRGNPVLKFVRNVPWEFGEVIPDYVLGQSTCALFLSLRYHNLHP
DYIHERLQSLGKNFALRVLLVQVDVKDPQQALKELAKMCILADCTLVLAW
SAEEAGRYLETYKAYEQKPADLLMEKLEQNFLSRATECLTTVKSVNKTDS
QTLLATFGSLEQLFTASREDLALCPGLGPQKARRLFEVLHEPFLKVPR

Ercc1 (Mus musculus) belongs to following protein families:
References:

Title Authors Journal
Evolution and mutagenesis of the mammalian excision repair gene ERCC-1. van Duin M, van den Tol J, Warmerdam P, Odijk H, Meijer D, Westerveld A, Bootsma D, Hoeijmakers JH Nucleic Acids Res June 24, 1988


Last modification of this entry: Oct. 6, 2010.

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