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Msh4 |
Protein FULL name:
mutS protein homolog 4 [Mus musculus].
Msh4 (Mus musculus) is product of expression of Msh4 gene.
FUNCTION: Involved in meiotic recombination. Required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.
SUBUNIT: Heterooligomer of MSH4 and MSH5.
TISSUE SPECIFICITY: Predominantly expressed in testis.
SIMILARITY: Belongs to the DNA mismatch repair mutS family.
| NCBI GenPept GI number(s): |
13994197 |
| Species: | Mus musculus |
Links to other databases:
| Database | ID | Link |
| Uniprot | Q99MT2 |
Q99MT2 |
| PFAM: | - |
Q99MT2 (Link - using uniprot id) |
| InterPro: | - |
Q99MT2 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MCCLFLRLRDYSTAHALSLPPCQRCGLQPWSARSHARRTLGVRKAGEMLR QEAASLSSSPRWTPSRRDAPCGRTLASASRPSTEGAMADRSSSSSSSPAP ASAPGSSFGNKRSYAIHRAASSFPVGTSSSSARDTTYPHTFRTPLSAGNP QRSGHKSWTPQVGYSATSSAVSAHAPSVIVAVVEGRGLARGEIGMASIDL KSPQIMLSQFADNTTYAKVITKLQVLSPLEIIMSNTACVVGNSTKLFTLI TENFKNVNFTTVQRKYFNETKGLEYIEQLCIAEFSSVLMEVQSRYYCLAA AAALLKYVEFIQNSVYAPKSLKIYFQGSEQTAMIDSSSAQNLELLVNNQD YRSNHTLFGVLNYTKTAGGSRRLRSNILEPLVDVETISMRLDCVQELLQD EELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTL ELVEPLKVTLKNCSTPLLRAYYGSLEDHRFGLILDKIKTVINDDARYMKG CLNMRTQKCYAVRSNISEFLDIARRTYTEIVDDIAGMIAQLAEKYSLPLR TSFSSSRGFFIQMTTDCAALSSDQLPSEFIKISKVKNSYSFTSADLIKMN ERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAH ACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPVANNTYITEGSNVLII TGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYASFRIAAQIFTRISTDDD IETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGISYAVC EHLLSIKAFTLFTTHFLELCHLDALYLNVENMHFEVQHVKNTSRNKDAIL YTYKLSRGLTEEKNYGLKAAEASSLPSSIVLDARDITTQITRQILQNQRS SPEMDRQRAVYHLATRLVQAARNSQLEPDRLRTYLSNLKKKYAGDFPRAV GLPEKTEE |
Msh4 (Mus musculus) belongs to following protein families:
References:
| Title | Authors | Journal |
| Mouse MutS homolog 4 is predominantly expressed in testis and interacts with MutS homolog 5. | Her C, Wu X, Bailey SM, Doggett NA | Mamm Genome Feb. 1, 2001 |
| Family of SRY/Sox proteins is involved in the regulation of the mouse Msh4 (MutS Homolog 4) gene expression. | Santucci-Darmanin S, Vidal F, Scimeca JC, Turc-Carel C, Paquis-Flucklinger V | Mol Reprod Dev Oct. 1, 2001 |
Last modification of this entry: Oct. 6, 2010.
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