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Msh5 |
Protein FULL name:
mutS homolog 5 [Mus musculus].
Msh5 (Mus musculus) is product of expression of Msh5 gene.
FUNCTION: Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis (By similarity).
SUBUNIT: Heterooligomer of MSH4 and MSH5. Interacts with HJURP (By similarity).
SIMILARITY: Belongs to the DNA mismatch repair mutS family.
| NCBI GenPept GI number(s): |
7305281 |
| Species: | Mus musculus |
Links to other databases:
| Database | ID | Link |
| Uniprot | Q9QUM7 |
Q9QUM7 |
| PFAM: | - |
Q9QUM7 (Link - using uniprot id) |
| InterPro: | - |
Q9QUM7 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MAFRATPGRTPPGPGPRSGIPSASFPSPQPPMAGPGGIEEEDEEEPAEIH LCVLWSSGYLGIAYYDTSDSTIHFMPDAPDHESLKLLQRVLDEINPQSVV TSAKQDEAMTRFLGKLASEEHREPKGPEIILLPSVDFGPEISKQRLLSGN YSFISDSMTATEKILFLSSIIPFDCVLTVRALGGLLKFLSRRRIGVELED YDVGVPILGFKKFVLTHLVSIDQDTYSVLQIFKSESHPSVYKVASGLKEG LSLFGILNRCRCKWGQKLLRLWFTRPTRELRELNSRLDVIQFFLMPQNLD MAQMLHRLLSHIKNVPLILKRMKLSHTKVSDWQVLYKTVYSALGLRDACR SLPQSIQLFQDIAQEFSDDLHHIASLIGKVVDFEESLAENRFTVLPNIDP DIDAKKRRLIGLPSFLTEVAQKELENLDSRIPSCSVIYIPLIGFLLSIPR LPFMVEASDFEIEGLDFMFLSEDKLHYRSARTKELDTLLGDLHCEIRDQE TLLMYQLQCQVLARASVLTRVLDLASRLDVLLALASAARDYGYSRPHYSP CIHGVRIRNGRHPLMELCARTFVPNSTDCGGDQGRVKVITGPNSSGKSIY LKQVGLITFMALVGSFVPAEEAEIGVIDAIFTRIHSCESISLGLSTFMID LNQVAKAVNNATEHSLVLIDEFGKGTNSVDGLALLAAVLRHWLALGPSCP HVFVATNFLSLVQLQLLPQGPLVQYLTMETCEDGEDLVFFYQLCQGVASA SHASHTAAQAGLPDPLIARGKEVSDLIRSGKPIKATNELLRRNQMENCQA LVDKFLKLDLEDPTLDLDIFISQEVLPAAPTIL |
Msh5 (Mus musculus) belongs to following protein families:
References:
| Title | Authors | Journal |
| Mammalian MutS homologue 5 is required for chromosome pairing in meiosis. | Edelmann W, Cohen PE, Kneitz B, Winand N, Lia M, Heyer J, Kolodner R, Pollard JW, Kucherlapati R | Nat Genet Feb. 1, 1999 |
| Identification and characterization of the mouse MutS homolog 5: Msh5. | Her C, Wu X, Wan W, Doggett NA | Mamm Genome Nov. 1, 1999 |
| Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region. | van Kooij M, de Groot K, van Vugt H, Aten J, Snoek M | Immunogenetics Oct. 1, 2001 |
| Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. | Xie T, Rowen L, Aguado B, Ahearn ME, Madan A, Qin S, Campbell RD, Hood L | Genome Res Dec. 1, 2003 |
Last modification of this entry: Oct. 6, 2010.
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