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Bujnicki Lab Homepage

Rev3l

Protein FULL name:

DNA polymerase zeta catalytic subunit [Mus musculus].


Rev3l (Mus musculus) is product of expression of Rev3l gene.






CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

SUBUNIT: Interacts with REV7 (By similarity).

SUBCELLULAR LOCATION: Nucleus (Potential).

SIMILARITY: Belongs to the DNA polymerase type-B family.


NCBI GenPept GI number(s): 153792337
Species: Mus musculus

Links to other databases:

Database ID Link
Uniprot Q61493 Q61493
PFAM: - Q61493 (Link - using uniprot id)
InterPro: - Q61493 (Link - using uniprot id)
CATH: - -
SCOP: - -
PDB: - -


Protein sequence:
MFSVRIVTADYYMASPLPGLDTCQSPLTQLPVKKVPVVRVFGATPAGQKT
CLHLHGIFPYLYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQH
VFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKCY
QPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGNASHATGLFKH
QLSGNSPAGTLFRWEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLD
IEAQIGGNPGLQAIWEDEKQRRRNRNESSQISQPESQDCRFVPATESEKQ
FQKRLQEVLKQNDFSVTLSGSVDYSNGSQEFSAELTLHSEILSPEMLPCS
PANMIEVHKDTDLSKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLS
ETPVFMGSSPDESLVHLLAGLESDGYQGEKNRMPLPCHSFGESQNPQNSD
DEENEPQIEKEEMELSVVMSQRWDSDIEEHCAKKRSLCRNAHRSSTEEDD
SSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIAT
SKLSVRPSIFHKDAATLEPPSSAKITFQCKHTSALSSHVLNKDGLTEDLS
QPNSTEKGRDNSVTFTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLP
VSSCESSVFDYEEDIPSVTRQVPSRKYSNMRKIEKDASCIHVNRHISETI
LGKNSFNFADLNHSKRKLSSEGNEKGNSTSLSGVFPSSLTENCDLLPSSG
ENRSMAHSLESITDESGLNKLKIRYEEFQEHKMEKPSLSQQAAHYMFFPS
VVLSNCLTRPQKLSPVTYKLQSGNKPSRLKLNKKKLIGLQETSTKSTETG
ATKDSCTHNDLYTGASEKENGLSSDSAKATHGTFENKPPTEHFIDCHFGD
GSLEAEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTQNSKISLPHPMEI
GENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKE
KQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSK
HKSAKKKPGKQHRTNSENIKRTLSFRKKRTHAVLSPPSPSYIAETEDCDL
SYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAAEKESMLFK
GPNVYNTKTVSPRVGKASRARAQVKKSKARLANSSVVTNKRNKRNQTTKL
VDDGKKKPRAKQKQRANEKSLSRKHAIPADEKMKPHSEAELTPNHQSVSE
LTSSSGAQALSKQKEMSQTGPAVDHPLPPAQPTGISAQQRLSNCFSSFLE
SKKSVDLRTFPSSRDDSHSSVVYSSIGPGISKINIQRSHNQSAMFTRKET
TLIQKSIFDLSNHLSQVAQSTQVCSGIISPKTEESSSTQKNCGSSMGKLN
EYRSSLESKPEQVCAPNFLHCKDSQQQTVSVSEQSKTSETCSPGNAASEE
SQTPNCFVTSLKSPIKQIAWEQKQRGFILDMSNFKPEKVKQRSLSEAISQ
TKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQSTNVVQDSTS
THQPDKNISVSNEHKKANKRTRPVTSPRKPRTPRRTKPKEQTPRRLKVDP
LNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEHNYNFDINTIG
QTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIDKSELLSHDRQS
CSEEKHHVSDSSPWIRASTLNPELFEKVAMDNNENHRHSQWKNSFHPLTS
HSNSIMESFCVQQAENCLTEKSRLNRSSVSKEVFLSLPQANSSDWIQGHN
RKEADQSLHSANTSFTTILSSPDGELVDAASEDLELYVSRNNDVLTPTPD
SSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAI
YQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWK
TAFSAMTQNPRPGSPLRNGQAVVNKESSNSHKMVEDKKIVIMPCKYAPSR
QLVQAWLQAKEEYERSKKLPKTELTPVTKSAENVSPSLNPGDTCAVSPQV
DKCPHTLSSSAHTKEEVSKSQIALQTSTTGCSQTLLAAASAAVPEEDEDD
NDNCYVSYSSPDSPGIPPWQQAASPDFRSLNGDDRHSSPGKELCSLAVEN
FLKPIKDGIQKSSCSESWEPQVISPIHARARTGKWDPLCLHSTPVMQRKF
LEKLPEATGLSPLSVEPKTQKLYNKKGSDADGLRRVLLTTQVENQFAAVN
TPKKETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHART
RRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQD
IRSQTPLLIRSGITGLEVTYAADEKALFQEITNIIKRYDPDILLGYEIQM
HSWGYLLQRAAALSVDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINI
VGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNK
TDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRG
SQYRVESMMLRIAKPMNYIPVTPSIQQRSQMRAPQCVPLIMEPESRFYSN
SVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPD
LLYQIRHDVTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYK
QDRALSRMLNARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIVHKARE
TLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAV
TATNPRPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKEPVFDAKGIETV
RRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFI
FAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIIYGTP
GLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSW
YQELPRIQKATSSSRSELEGRKGTISQYFTTLHCPVCDDLTQHGICSKCR
SQPQHVAIILNQEIRELERKQEQLIKICRNCTGSFDRHIPCVSLNCPVLF
KLSRVNRELSKAPYLRQLLDQF

Rev3l (Mus musculus) belongs to following protein families:
References:

Title Authors Journal
Molecular characterization of seizure-related genes isolated by differential screening. Kajiwara K, Nagawawa H, Shimizu-Nishikawa S, Ookuri T, Kimura M, Sugaya E Biochem Biophys Res Commun Jan. 27, 1996
Molecular cloning, expression and chromosomal localisation of the mouse Rev3l gene, encoding the catalytic subunit of polymerase zeta. Van Sloun PP, Romeijn RJ, Eeken JC Mutat Res March 10, 1999


Last modification of this entry: Oct. 6, 2010.

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