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Protein FULL name: DNA polymerase zeta catalytic subunit [Mus musculus].
Rev3l (Mus musculus) is product of expression of
Rev3l
gene.
CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) =
diphosphate + DNA(n+1).
SUBUNIT: Interacts with REV7 (By similarity).
SUBCELLULAR LOCATION: Nucleus (Potential).
SIMILARITY: Belongs to the DNA polymerase type-B family.
Links to other databases:
Protein sequence:
MFSVRIVTADYYMASPLPGLDTCQSPLTQLPVKKVPVVRVFGATPAGQKT
CLHLHGIFPYLYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQH
VFKVSLVSGMPFYGYHEKERHFMKIYLYNPAMVKRICELLQSGAIMNKCY
QPHEAHIPYLLQLFIDYNLYGMNLINLAAVKFRKARRKGNASHATGLFKH
QLSGNSPAGTLFRWEEDEIPSSLLLEGVEPLSTCELEVDAVAADILNRLD
IEAQIGGNPGLQAIWEDEKQRRRNRNESSQISQPESQDCRFVPATESEKQ
FQKRLQEVLKQNDFSVTLSGSVDYSNGSQEFSAELTLHSEILSPEMLPCS
PANMIEVHKDTDLSKGNTKHKVEEALINEEAILNLIENSQTFQPLTQRLS
ETPVFMGSSPDESLVHLLAGLESDGYQGEKNRMPLPCHSFGESQNPQNSD
DEENEPQIEKEEMELSVVMSQRWDSDIEEHCAKKRSLCRNAHRSSTEEDD
SSSEEEMEWTDNSLLFANLSIPQLDGTADENSDNPLNNENSRAHSSVIAT
SKLSVRPSIFHKDAATLEPPSSAKITFQCKHTSALSSHVLNKDGLTEDLS
QPNSTEKGRDNSVTFTKESTYSMKYSGSLSSTVHSDNSHKEICKKDKSLP
VSSCESSVFDYEEDIPSVTRQVPSRKYSNMRKIEKDASCIHVNRHISETI
LGKNSFNFADLNHSKRKLSSEGNEKGNSTSLSGVFPSSLTENCDLLPSSG
ENRSMAHSLESITDESGLNKLKIRYEEFQEHKMEKPSLSQQAAHYMFFPS
VVLSNCLTRPQKLSPVTYKLQSGNKPSRLKLNKKKLIGLQETSTKSTETG
ATKDSCTHNDLYTGASEKENGLSSDSAKATHGTFENKPPTEHFIDCHFGD
GSLEAEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTQNSKISLPHPMEI
GENLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKE
KQVILTEEKMELYKKLAPLKDFWPKVPDSPATKYPIYPLTPKKSHRRKSK
HKSAKKKPGKQHRTNSENIKRTLSFRKKRTHAVLSPPSPSYIAETEDCDL
SYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIMAAAEKESMLFK
GPNVYNTKTVSPRVGKASRARAQVKKSKARLANSSVVTNKRNKRNQTTKL
VDDGKKKPRAKQKQRANEKSLSRKHAIPADEKMKPHSEAELTPNHQSVSE
LTSSSGAQALSKQKEMSQTGPAVDHPLPPAQPTGISAQQRLSNCFSSFLE
SKKSVDLRTFPSSRDDSHSSVVYSSIGPGISKINIQRSHNQSAMFTRKET
TLIQKSIFDLSNHLSQVAQSTQVCSGIISPKTEESSSTQKNCGSSMGKLN
EYRSSLESKPEQVCAPNFLHCKDSQQQTVSVSEQSKTSETCSPGNAASEE
SQTPNCFVTSLKSPIKQIAWEQKQRGFILDMSNFKPEKVKQRSLSEAISQ
TKALSQCKNQNVSTPSVFGEGQSGLAVLKELLQKRQQKAQSTNVVQDSTS
THQPDKNISVSNEHKKANKRTRPVTSPRKPRTPRRTKPKEQTPRRLKVDP
LNLQTSGHLDNSLSDDSPILFSDPGFESCYSLEDSLSPEHNYNFDINTIG
QTGFCSFYSGSQFVPADQNLPQKFLSDAVQDLFPGQAIDKSELLSHDRQS
CSEEKHHVSDSSPWIRASTLNPELFEKVAMDNNENHRHSQWKNSFHPLTS
HSNSIMESFCVQQAENCLTEKSRLNRSSVSKEVFLSLPQANSSDWIQGHN
RKEADQSLHSANTSFTTILSSPDGELVDAASEDLELYVSRNNDVLTPTPD
SSPRSTSSPLQSKNGSFTPRTAHILKPLMSPPSREEIVATLLDHDLSEAI
YQEPFCSNPSDVPEKPREIGGRLLMVETRLPNDLIEFEGDFSLEGLRLWK
TAFSAMTQNPRPGSPLRNGQAVVNKESSNSHKMVEDKKIVIMPCKYAPSR
QLVQAWLQAKEEYERSKKLPKTELTPVTKSAENVSPSLNPGDTCAVSPQV
DKCPHTLSSSAHTKEEVSKSQIALQTSTTGCSQTLLAAASAAVPEEDEDD
NDNCYVSYSSPDSPGIPPWQQAASPDFRSLNGDDRHSSPGKELCSLAVEN
FLKPIKDGIQKSSCSESWEPQVISPIHARARTGKWDPLCLHSTPVMQRKF
LEKLPEATGLSPLSVEPKTQKLYNKKGSDADGLRRVLLTTQVENQFAAVN
TPKKETSQIDGPSLNNTYGFKVSIQNLQEAKALHEIQNLTLISVELHART
RRDLQPDPEFDPICALFYCISSDTPLPDTEKTELTGVIVIDKDKTVTHQD
IRSQTPLLIRSGITGLEVTYAADEKALFQEITNIIKRYDPDILLGYEIQM
HSWGYLLQRAAALSVDLCQMISRVPDDKIENRFAAERDDYGSDTMSEINI
VGRITLNLWRIMRNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNK
TDLYRWKMVDHYVSRVRGNLQMLEQLDLIGKTSEMARLFGIQFLHVLTRG
SQYRVESMMLRIAKPMNYIPVTPSIQQRSQMRAPQCVPLIMEPESRFYSN
SVLVLDFQSLYPSIVIAYNYCFSTCLGHVENLGKYDEFKFGCTSLRVPPD
LLYQIRHDVTVSPNGVAFVKPSVRKGVLPRMLEEILKTRLMVKQSMKSYK
QDRALSRMLNARQLGLKLIANVTFGYTAANFSGRMPCIEVGDSIVHKARE
TLERAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAV
TATNPRPVKLKFEKVYLPCVLQTKKRYVGYMYETLDQKEPVFDAKGIETV
RRDSCPAVSKILERSLKLLFETRDISLIKQYVQRQCMKLVEGKASIQDFI
FAKEYRGSFSYRPGACVPALELTRKMLAYDRRSEPRVGERVPYVIIYGTP
GLPLIQLIRRPAEVLQDPTLRLNATYYITKQILPPLARIFSLIGIDVFSW
YQELPRIQKATSSSRSELEGRKGTISQYFTTLHCPVCDDLTQHGICSKCR
SQPQHVAIILNQEIRELERKQEQLIKICRNCTGSFDRHIPCVSLNCPVLF
KLSRVNRELSKAPYLRQLLDQF
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Rev3l (Mus musculus) belongs to following protein families:
References:
Title
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Authors
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Journal
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Molecular characterization of seizure-related genes isolated by differential screening.
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Kajiwara K, Nagawawa H, Shimizu-Nishikawa S, Ookuri T, Kimura M, Sugaya E
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Biochem Biophys Res Commun
Jan. 27, 1996
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Molecular cloning, expression and chromosomal localisation of the mouse Rev3l gene, encoding the catalytic subunit of polymerase zeta.
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Van Sloun PP, Romeijn RJ, Eeken JC
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Mutat Res
March 10, 1999
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Last modification of this entry: Oct. 6, 2010.
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