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Polg |
Protein FULL name:
DNA polymerase subunit gamma-1 [Mus musculus].
Polg (Mus musculus) is product of expression of Polg gene.
FUNCTION: Involved in the replication of mitochondrial DNA.
CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
COFACTOR: Magnesium (By similarity).
SUBUNIT: Heterotrimer composed of a catalytic subunit and an homodimer of accessory subunits.
SUBCELLULAR LOCATION: Mitochondrion.
SIMILARITY: Belongs to the DNA polymerase type-A family.
| NCBI GenPept GI number(s): |
87080815 |
| Species: | Mus musculus |
Links to other databases:
| Database | ID | Link |
| Uniprot | P54099 |
P54099 |
| PFAM: | - |
P54099 (Link - using uniprot id) |
| InterPro: | - |
P54099 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MSRLLWKKVAGAKVASGPVPATARWVSSSVLDPVPSDGRPPSQMPSSENG QLRLNPLLIQMLSRGLHEQIFGCGGEMPDEAAVQRSVEHLQKHGLWGQPA TPLPDVELRLPRLFGGNLDQHFRLLAQKQSLPYLEAAASLLEAQLPPEPK SWAWAEGWTRYGPEGEAEPVAIPEERALVFDVEVCLAEGTCPTLAVAISP SAWYSWCSRRLVEERYSWTSQLSPADLIPLGGSTSASSSTKQDGQEQLVV GHNVSFDRAHIREQYLIQDSRMRFLDTMSMHMAISGLSSFQRSLWMGAKQ GKHKTQQSTKRGQKSPRKANGPAISSWDWMDISSANNLADVHNLYVGGPP LEKEPRELFVKGSMRDIRENFQDLMQYCARDVWATFEVFQQQLPLFLERC PHPVTLAGMLEMGVSYLPVNQNWERYLTEAQNTYEELQREMKKSLMDLAN DACQLLSGERYKEDPWLWDLEWDLQEFKQKKAKKVKKPASASKLPIEGAG PFGDPMDQEDPGPPSEEEELQRSVTAHNRLQQLRSTTDLLPKRPQHLPGH PGWYRKLCPRLDDPAWAPGPSLLSLQMRVTPKLMALTWDGFPLHYSDSHG WGYLVPGRRDNLTEPPVSPTVESAAVTCPYRAIESLYRKHCLEQGKQQLE PQEVDLAEEFLLTDSSAMWQTVEELGCLDVEAEAKMENSGLSQPLVLPAA CAPKSSQPTYHHGNGPYNDVNIPGCWFFKLPHKDGNNYNVGSPFAKDFLP KMEDGTLQAGPGGASGPRALEINKMISFWRNAHKRISSQMVVWLPRSALP RVVTRHPSFDEEGHYGAILPQVVTAGTITRRAVEPTWLTASNARPDRVGS ELKAMVQAPPGYVLVGADVDSQELWIAAVLGDAHFAGMHGCTAFGWMTLQ GRKSRGTDLHSKTAATVGISREHAKIFNYGRIYGAGQSFAERLLMQFNHR LTRQEAAEKAQQMYAVTKGLRRYRLSADGEWLVKQLNLPVDRTEDGWVSL QDLRMIRREASRKSRWKKWEVASERAWTGGTESEMFNKLESIAMSDTPRT PVLGCCISRALEPSVVQGEFITSRVNWVVQSSAVDYLHLMLVAMKWLFEE FAIDGRFCISIHDEVRYLVREEDRYRAALALQITNLLTRCMFAYKLGLND LPQSVAFFSAVDIDQCLRKEVTMDCKTPSNPTGMERRYGIPQGEALDIYQ IIELTKGSLEKRSQPGP |
Polg (Mus musculus) is able to recognize following damages:
Polg (Mus musculus) belongs to following protein families:
References:
| Title | Authors | Journal |
| Genomic structure of murine mitochondrial DNA polymerase-gamma. | Mott JL, Denniger G, Zullo SJ, Zassenhaus HP | DNA Cell Biol Oct. 1, 2000 |
Last modification of this entry: Oct. 6, 2010.
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