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Poln |
Protein FULL name:
DNA polymerase nu [Mus musculus].
Poln (Mus musculus) is product of expression of Poln gene.
CATALYTIC ACTIVITY: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
SUBCELLULAR LOCATION: Nucleus (By similarity).
TISSUE SPECIFICITY: Expressed only in testis namely in primary spermatocytes and in round spermatids.
SIMILARITY: Belongs to the DNA polymerase type-A family.
SEQUENCE CAUTION: Sequence=AAN39837.2; Type=Erroneous initiation; Sequence=BAE21491.1; Type=Erroneous initiation;
| NCBI GenPept GI number(s): |
46309579 |
| Species: | Mus musculus |
Links to other databases:
| Database | ID | Link |
| Uniprot | Q7TQ07 |
Q7TQ07 |
| PFAM: | - |
Q7TQ07 (Link - using uniprot id) |
| InterPro: | - |
Q7TQ07 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MKMENYEACVGFDVCEIPLSAVAQKIMSAMRSGDFMDSRNEGESTNTSKV AKKSSVHYSVLAEHEETQSLGTKNPESLITQTPRGSIELCPQPSITKLTC QLSAGQVQNSISSLGLSSYLIPQCDQEASVLPNMEHKRQHFLKENIGKED KDNSSLKRKYITCSKSSEKASKHTALEKDTDGTESWPNSRDTRALGERLC DVRYLGDLAKAQLMDALKQAAALVVTLMYKDGSTQLSAKEALTCTVKGIV VLLKSHVGNSTLTLPAHGGALEKDFISEDHCVYIHTEHSPFWDPKQEAHS LFVRNILFWTLRCKCPVVCFNAKDFVRTVLQLYGEDGSWKHVADFVGLDP RVAAWLIDPSDTAPSFEDLVAKHLEKSITVKPSSTFREASRNTLSQNVFM NLKILYDLTMDLCSKLKAYGLWQLFCTLELPLIPILAVMENHKIPVDKEE MERTSALLGARLKELEQEAHFVAGEQFLIMSNNQLREILFGKLKLHLLSQ RKHLPRTGLQNQLSTSEAMLNSLQDLHPLPKLILEYRQVHKIKSTFIDGL LAYMKKGSISSTWNQTGTVTGRLSAKHPNIQGISKHPIKISKPWNFKGKE EETVTISPRTLFVSSEGHTFLAADFSQIELRILAHLSGDPELLKLFQESE RDDVFSTLTSQWKDIPIERVTHMDREQTKKVVYSVVYGAGKERLAACLGV TVLEATHFLERFLQKYKKIKDFAQTVIGQCHSAGYVTSILGRRRPLPRIC AQDQQLRAQAERQAVNFVVQGSAADLCKLAMIRISTAVATSPTLTARLVA QIHDELLFEVEDTQVPEFAALVRRIMESLQQVQTLELQLQVPLKVNLSVG RSWGHLTPLQEILGSA |
Poln (Mus musculus) is able to recognize following damages:
Poln (Mus musculus) belongs to following protein families:
References:
| Title | Authors | Journal |
| POLN, a nuclear PolA family DNA polymerase homologous to the DNA cross-link sensitivity protein Mus308. | Marini F, Kim N, Schuffert A, Wood RD | J Biol Chem Aug. 22, 2003 |
| The transcriptional landscape of the mammalian genome. | Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schonbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y | Science Sept. 2, 2005 |
Last modification of this entry: Oct. 6, 2010.
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