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T7P1.7 |
Protein FULL name:
putative DNA helicase; 33057-26178 [Arabidopsis thaliana].
T7P1.7 (Arabidopsis thaliana) is product of expression of ATRECQ4B gene.
FUNCTION: 3'-5' DNA helicase that may play a role in the repair of DNA (By similarity). Required to promote but not to suppress crossovers.
CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
COFACTOR: Magnesium or manganese (By similarity).
SUBCELLULAR LOCATION: Nucleus (By similarity).
TISSUE SPECIFICITY: Mostly expressed in roots, seedlings, shoots, shoot apical mersitem, flowers, and siliques.
INDUCTION: Repressed by cold.
DISRUPTION PHENOTYPE: Not mutagen-sensitive, and impaired in hyperrecombination (HR).
SIMILARITY: Belongs to the helicase family. RecQ subfamily.
SIMILARITY: Contains 1 helicase ATP-binding domain.
SIMILARITY: Contains 1 helicase C-terminal domain.
SIMILARITY: Contains 1 HRDC domain.
SEQUENCE CAUTION: Sequence=AAG51646.1; Type=Erroneous gene model prediction;
| NCBI GenPept GI number(s): |
12323338 |
| Species: | Arabidopsis thaliana |
Links to other databases:
| Database | ID | Link |
| Uniprot | Q9FT70 |
Q9FT70 |
| PFAM: | - |
Q9FT70 (Link - using uniprot id) |
| InterPro: | - |
Q9FT70 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MAARSIENIAPVTVQTLARPQIEKAWCTLINLSINNTYLRPGITPAIDND STSRTSSTKGSTFKVTSNADGSFCAHNHPEHSQRSVRGTAKSIDSFSSSS VGDNKIIIDKVPRVNYEVRDSVTVTNGMEMPPIKNSAQLARPVEPREVSL GEIDYDDIMENRLTSTCANFGAQIIDVDQIAMEHCPSTCTKQPSVSKFVD IFTSRREEEQGLPPEICSNCSHGIKLLHKPIGFLMLFALISTQLGLCPEA STHVEQMKDTLLAISNEILDNTYDLGPDHVEQLHQKRLLLKKQIQQLEIL IHNKERKKSQCLVSIPSHNTQYETPQTTNLEVVYGQTDSPTHVKEQGRCV TDNWNMPRDYLVSKERYDISSGSEEREQSVSEVIDVTDTESSNDKKWTSS DFPWTKNLEVYNKLVFGNHSFRPNQREIINATMSGCDVFLPALLCAGITL VISPLVSLIQDQIMNLLQTNISAASLSAGMEWAEQLEILQELSSEKSKYK LLYVTPEKVAKSESLLRHLEILNSRSLLARFVIDEAHCVSQWGHDFRPDY QGLGVLKQKFPNIPMLALTATATTSVKEDVVQALGLVNCVVFRQSFNRPN LWYSVVPKTNKCLEDIDKFIRENHFDECGIIYCLSRMDCEKVTEALRVFG HKAAFYHGSMDPGKRAFVQKQWSKDEINIICATVAFGMGINKPDVRFVIH HSLPKSIEGYHQECGRAGRDGQRSSCVLYYSYTDYIRVKHMISQGGLGQG QMKMGYNCKASSGRMLETNTENLLRMVSYCENEVDCRRFLQLVHLGEKFD STNCKNTCDNCSSSKILIDKDVTVIARQLVALVKLTGERFSSAHIVEIYR GSLNQSVKRNRQDTLHLHGAGKHLTKSEASRILHYLVTEDILAEGVKKSE LYGSVSSLLKNLSGILLTALKNLRTDIVKESPDLVMAYHIFGNATLKEIS KRLPRTKEELLDINGLGKAKVSKYGDRLLETIDSTINDHYKTRPGSGKRR RDENVNPNVAEDDDPDWSASQSHKKVVKNKK |
References:
| Title | Authors | Journal |
| Molecular characterisation of RecQ homologues in Arabidopsis thaliana. | Hartung F, Plchova H, Puchta H | Nucleic Acids Res Nov. 1, 2000 |
| Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. | Theologis A, Ecker JR, Palm CJ, Federspiel NA, Kaul S, White O, Alonso J, Altafi H, Araujo R, Bowman CL, Brooks SY, Buehler E, Chan A, Chao Q, Chen H, Cheuk RF, Chin CW, Chung MK, Conn L, Conway AB, Conway AR, Creasy TH, Dewar K, Dunn P, Etgu P, Feldblyum TV, Feng J, Fong B, Fujii CY, Gill JE, Goldsmith AD, Haas B, Hansen NF, Hughes B, Huizar L, Hunter JL, Jenkins J, Johnson-Hopson C, Khan S, Khaykin E, Kim CJ, Koo HL, Kremenetskaia I, Kurtz DB, Kwan A, Lam B, Langin-Hooper S, Lee A, Lee JM, Lenz CA, Li JH, Li Y, Lin X, Liu SX, Liu ZA, Luros JS, Maiti R, Marziali A, Militscher J, Miranda M, Nguyen M, Nierman WC, Osborne BI, Pai G, Peterson J, Pham PK, Rizzo M, Rooney T, Rowley D, Sakano H, Salzberg SL, Schwartz JR, Shinn P, Southwick AM, Sun H, Tallon LJ, Tambunga G, Toriumi MJ, Town CD, Utterback T, Van Aken S, Vaysberg M, Vysotskaia VS, Walker M, Wu D, Yu G, Fraser CM, Venter JC, Davis RW | Nature Dec. 14, 2000 |
| Arabidopsis RecQsim, a plant-specific member of the RecQ helicase family, can suppress the MMS hypersensitivity of the yeast sgs1 mutant. | Bagherieh-Najjar MB, de Vries OM, Kroon JT, Wright EL, Elborough KM, Hille J, Dijkwel PP | Plant Mol Biol May 1, 2003 |
| The RecQ gene family in plants. | Hartung F, Puchta H | J Plant Physiol Jan. 1, 2006 |
| Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana. | Hartung F, Suer S, Puchta H | Proc Natl Acad Sci U S A Nov. 20, 2007 |
Last modification of this entry: Oct. 6, 2010.
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