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Rad28p |
Protein FULL name:
Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair
Rad28p (Saccharomyces cerevisiae) is product of expression of RAD28 gene.
Rad28p is involved in:
NER in Saccharomyces cerevisiae
- Rad28 joins RNA polymerase in Saccharomyces cerevisiae
- recruitment of TFIIH and Rad14 in Saccharomyces cerevisiae
- Rad25 and Rad3 unwind DNA in presence of RNAP in Saccharomyces cerevisiae
- RPA binds to undamaged strand in Saccharomyces cerevisiae
- Rad2 joins the complex in Saccharomyces cerevisiae
- recruitment of Rad1/Rad10 complex in Saccharomyces cerevisiae
Keywords:
FUNCTION: Involved in transcription-coupled repair nucleotide excision repair (NER) of UV-induced DNA lesions.
SUBCELLULAR LOCATION: Nucleus (Probable).
SIMILARITY: Contains 5 WD repeats.
| NCBI GenPept GI number(s): |
6320233 |
| Species: | Saccharomyces cerevisiae |
Links to other databases:
| Database | ID | Link |
| Uniprot | Q12021 |
Q12021 |
| PFAM: | - |
Q12021 (Link - using uniprot id) |
| InterPro: | - |
Q12021 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MDPFLEFRVGNISLNEFYRRTIQSEFERILEDPLSNMKNYRFSKQSNYST KEKTPLSIGVNCLDIDDTGQVLLGGGDDGSLSIWGLDESLHRNDEGEQEL INKRLNYIKRQPHQSDDEPAQIMGYKNKRTRINDNNTMRLVHSFQTQRNK YRMYRQSSAAVPVQRSHISNKTDSPIGFSETLSETDSEASISHHKYGITT LKWYKADNGMFFTGSNDKTVKIWDTNRFEAVQDINLGYKINQIDNNVVDD SSLLVVASEDYYPRLIDLRTMNSGVTALGMGNQTRMQSEILCCKFNPVRE QIIACGDMEGGVKLWDLRMRNRLYSELKRNKNRFKTINNDDNDDQSDVYF SSNQSKAHLRCCSDIVWNSEGSELCSVGMDGKLNVWRPFTEILQPEGLAS YSQLGTQDLSRIKYKKRVSRRLLWFDKFLLCITDNGEVEIYNTEEKKLWN KLEYPMVNQVKKNQASHCQFSSMIVQTNIMNSVGLKLFFGTNNNTVSDGG SIFECS |
Rad28p (Saccharomyces cerevisiae) belongs to following protein families:
References:
| Title | Authors | Journal |
| Molecular cloning and characterization of Saccharomyces cerevisiae RAD28, the yeast homolog of the human Cockayne syndrome A (CSA) gene. | Bhatia PK, Verhage RA, Brouwer J, Friedberg EC | J Bacteriol Oct. 1, 1996 |
| The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. | Jacq C, Alt-Morbe J, Andre B, Arnold W, Bahr A, Ballesta JP, Bargues M, Baron L, Becker A, Biteau N, Blocker H, Blugeon C, Boskovic J, Brandt P, Bruckner M, Buitrago MJ, Coster F, Delaveau T, del Rey F, Dujon B, Eide LG, Garcia-Cantalejo JM, Goffeau A, Gomez-Peris A, Zaccaria P, et al. | Nature May 1, 1997 |
| Recovery of RNA polymerase II synthesis following DNA damage in mutants of Saccharomyces cerevisiae defective in nucleotide excision repair. | Reagan MS, Friedberg EC | Nucleic Acids Res Nov. 1, 1997 |
Last modification of this entry: Oct. 19, 2010.
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