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ung
Unnamed Gene ID: 947067
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Known also as: ECK2578; JW2564;
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UDG and Ndk form a complex (Goswami, 2006). [More information is available at EcoGene: EG11058]. Uracil can be generated in DNA as a result of misincorporation by DNA polymerase, spontaneous deamination of cytosine, and deamination of cytosine induced by bisulfite or nitrous acid. [More information is available at EcoCyc: EG11058].
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Gene sequence:
Proteins coded by this gene:
References:
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Authors
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Title
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Journal
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el-Hajj HH, Wang L, Weiss B
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Multiple mutant of Escherichia coli synthesizing virtually thymineless DNA during limited growth.
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J Bacteriol
July 1, 1992
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Lundquist AJ, Beger RD, Bennett SE, Bolton PH, Mosbaugh DW
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Site-directed mutagenesis and characterization of uracil-DNA glycosylase inhibitor protein. Role of specific carboxylic amino acids in complex formation with Escherichia coli uracil-DNA glycosylase.
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J Biol Chem
Aug. 22, 1997
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Saparbaev M, Laval J
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3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase.
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Proc Natl Acad Sci U S A
July 21, 1998
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Ravishankar R, Bidya Sagar M, Roy S, Purnapatre K, Handa P, Varshney U, Vijayan M
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X-ray analysis of a complex of Escherichia coli uracil DNA glycosylase (EcUDG) with a proteinaceous inhibitor. The structure elucidation of a prokaryotic UDG.
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Nucleic Acids Res
Nov. 1, 1998
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Putnam CD, Shroyer MJ, Lundquist AJ, Mol CD, Arvai AS, Mosbaugh DW, Tainer JA
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Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase.
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J Mol Biol
March 26, 1999
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Last modification of this entry: Oct. 6, 2010.
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