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Ung |
Protein FULL name:
uracil DNA glycosylase [Escherichia coli].
Ung (Escherichia coli strain K-12 substr. MG1655) is product of expression of ung gene.
Ung is involved in:
BER in Escherichia coli strain K-12 substr. MG1655
Keywords:
FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
CATALYTIC ACTIVITY: Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.
SUBUNIT: Monomer.
INTERACTION: P08957:hsdM; NbExp=1; IntAct=EBI-559403, EBI-878571; P0A763:ndk; NbExp=3; IntAct=EBI-559403, EBI-370139;
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: Belongs to the uracil-DNA glycosylase family.
| NCBI GenPept GI number(s): |
148149 |
| Species: | Escherichia coli |
Links to other databases:
| Database | ID | Link |
| Uniprot | P12295 |
P12295 |
| PFAM: | - |
P12295 (Link - using uniprot id) |
| InterPro: | - |
P12295 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRF TELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTI PGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVIS LINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGC NHFVLANQWLEQRGETPIDWMPVLPAESE |
Ung (Escherichia coli strain K-12 substr. MG1655) is able to recognize following damages:
Last modification of this entry: Oct. 15, 2010.
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