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Ung1p is involved in:
BER in Saccharomyces cerevisiae
FUNCTION: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
CATALYTIC ACTIVITY: Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.
SUBCELLULAR LOCATION: Nucleus. Mitochondrion.
MISCELLANEOUS: Present with 4820 molecules/cell in log phase SD medium.
SIMILARITY: Belongs to the uracil-DNA glycosylase family.
Links to other databases:
Ung1p (Saccharomyces cerevisiae) is able to recognize following damages:
Ung1p (Saccharomyces cerevisiae) belongs to following protein families:
Last modification of this entry: Oct. 6, 2010.
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