Welcome! Click here to login or here to register.
 |
|||||||||||||||||||
|
|||||||||||||||||||
 |
|||||||||||||||||||
DNA with damaged base
[Homo sapiens]
| The damage that appears can be either oxidized or ring-saturated base recognized by bifunctional glycosylases (with AP lyase activity) or deaminated, alkylated or mismatched base recognized by monofunctional glycosylase. |
DNA with damaged base is part of following pathways: This DNA state is a previous state in the following reactions:
| Reaction | Previous state | Following state |
| Monofunctional glycosylase recognizes damaged DNA in Homo sapiens | DNA with damaged base in Homo sapiens | damaged DNA with monofunctional glycosylase (MUTYH) [LP-BER] in Homo sapiens |
| Bifunctional glycosylase recognizes damaged DNA in Homo sapiens | DNA with damaged base in Homo sapiens | damaged DNA with bifunctional glycosylase (with AP lyase activity) [SP-BER] in Homo sapiens |
Add your own comment!
There is no comment yet.
|
|
|
|