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DNA with damaged base removed by bifunctional glysosylase (with AP lyase activity) [SP-BER]
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Reaction | Previous state | Following state |
Lesion recognition and removal by bifunctional glycosylase in Homo sapiens | damaged DNA with bifunctional glycosylase (with AP lyase activity) [SP-BER] in Homo sapiens | DNA with damaged base removed by bifunctional glysosylase (with AP lyase activity) [SP-BER] in Homo sapiens |
Reaction | Previous state | Following state |
Strand scission by APEX/pol beta/XRCC1/PARP/lig3 complex in Homo sapiens | DNA with damaged base removed by bifunctional glysosylase (with AP lyase activity) [SP-BER] in Homo sapiens | Scissored DNA strand with APEX/pol beta/PARP/XRCC1/Lig3 complex [SP-BER] in Homo sapiens |