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Bujnicki Lab Homepage

Heteroduplex DNA with nick 5' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex, bound by ExoI (proximal site)

[Homo sapiens]





Heteroduplex DNA with nick 5' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex, bound by ExoI (proximal site) is part of following pathways: This DNA state is a resulting state in the following reactions:

Reaction Previous state Following state
ExoI loads onto heteroduplex DNA with nick 5' to mismatch (on proximal site) in Homo sapiens Mismatch in heteroduplex DNA with nick 5' to mismatch and nicks around mismatch bound by MutSalpha-MutLalpha complex in Homo sapiens Heteroduplex DNA with nick 5' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex, bound by ExoI (proximal site) in Homo sapiens

This DNA state is a previous state in the following reactions:

Reaction Previous state Following state
ExoI excises errorenous strand heteroduplex DNA with nick 5' to mismatch (proximal site) in Homo sapiens Heteroduplex DNA with nick 5' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex, bound by ExoI (proximal site) in Homo sapiens Heteroduplex DNA with nick 5' to mismatch and nicks around mismatch, and with bound MutSalpha-MutLalpha complex and ExoI, with partially excised errorenous strand (proximal site) in Homo sapiens

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