REPAIRtoire - a database of DNA repair pathways

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Bujnicki Lab Homepage

Msh2

mutS homolog 2 (E. coli)

On chromosome: 17 45.9 cM
Known also as: AI788990;


NCBI Gene ID: 17685
NCBI Ensembl Id: ENSMUSG00000024151
Species: Mus musculus

Mus musculus mutS homolog 2 (E. coli) (Msh2).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
de Wind N, Dekker M, Claij N, Jansen L, van Klink Y, Radman M, Riggins G, van der Valk M, van't Wout K, te Riele H HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions. Nat Genet Nov. 1, 1999
Martin A, Li Z, Lin DP, Bardwell PD, Iglesias-Ussel MD, Edelmann W, Scharff MD Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination. J Exp Med Oct. 20, 2003
Kolas NK, Svetlanov A, Lenzi ML, Macaluso FP, Lipkin SM, Liskay RM, Greally J, Edelmann W, Cohen PE Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I. J Cell Biol Nov. 7, 2005
Yoshioka K, Yoshioka Y, Hsieh P ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts. Mol Cell May 19, 2006

Last modification of this entry: Oct. 6, 2010.

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