REPAIRtoire - a database of DNA repair pathways

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Dclre1a

DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)

On chromosome: 19
Known also as: Pso2; SNM1; SMN1a; mSNM1; AU022226; KIAA0086; mKIAA0086; 2810043H12Rik;


NCBI Gene ID: 55947
NCBI Ensembl Id: ENSMUSG00000025077
Species: Mus musculus

Mus musculus DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae) (Dclre1a).


Gene sequence:
[Download sequence]

Proteins coded by this gene:
References:

Authors Title Journal
Dronkert ML, de Wit J, Boeve M, Vasconcelos ML, van Steeg H, Tan TL, Hoeijmakers JH, Kanaar R Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C. Mol Cell Biol July 1, 2000
Ahkter S, Richie CT, Zhang N, Behringer RR, Zhu C, Legerski RJ Snm1-deficient mice exhibit accelerated tumorigenesis and susceptibility to infection. Mol Cell Biol Nov. 1, 2005
Hemphill AW, Bruun D, Thrun L, Akkari Y, Torimaru Y, Hejna K, Jakobs PM, Hejna J, Jones S, Olson SB, Moses RE Mammalian SNM1 is required for genome stability. Mol Genet Metab May 1, 2008
Akhter S, Legerski RJ SNM1A acts downstream of ATM to promote the G1 cell cycle checkpoint. Biochem Biophys Res Commun Dec. 5, 2008

Last modification of this entry: Oct. 6, 2010.

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