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Poli
polymerase (DNA directed), iota
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On chromosome: 18 44.0 cM
Known also as: Rad30b;
Mus musculus polymerase (DNA directed), iota (Poli).
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Gene sequence:
Proteins coded by this gene:
References:
Authors
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Title
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Journal
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McDonald JP, Frank EG, Plosky BS, Rogozin IB, Masutani C, Hanaoka F, Woodgate R, Gearhart PJ
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129-derived strains of mice are deficient in DNA polymerase iota and have normal immunoglobulin hypermutation.
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J Exp Med
Aug. 18, 2003
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Bienko M, Green CM, Crosetto N, Rudolf F, Zapart G, Coull B, Kannouche P, Wider G, Peter M, Lehmann AR, Hofmann K, Dikic I
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Ubiquitin-binding domains in Y-family polymerases regulate translesion synthesis.
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Science
Dec. 16, 2005
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Martomo SA, Yang WW, Vaisman A, Maas A, Yokoi M, Hoeijmakers JH, Hanaoka F, Woodgate R, Gearhart PJ
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Normal hypermutation in antibody genes from congenic mice defective for DNA polymerase iota.
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DNA Repair (Amst)
March 7, 2006
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Ohkumo T, Kondo Y, Yokoi M, Tsukamoto T, Yamada A, Sugimoto T, Kanao R, Higashi Y, Kondoh H, Tatematsu M, Masutani C, Hanaoka F
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UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota.
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Mol Cell Biol
Oct. 1, 2006
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Dumstorf CA, Clark AB, Lin Q, Kissling GE, Yuan T, Kucherlapati R, McGregor WG, Kunkel TA
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Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer.
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Proc Natl Acad Sci U S A
Nov. 28, 2006
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Last modification of this entry: Oct. 6, 2010.
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