REPAIRtoire - a database of DNA repair pathways

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Unnamed Gene ID: 946227

Known also as: ECK0953; JW0945; srjB;

NCBI Gene ID: 946227
Species: Escherichia coli strain K-12 substr. MG1655

Overexpression causes filamentous biofilm formation. [More information is available at EcoGene: EG10426]. The HelD protein, DNA helicase IV, is an ATP-dependent 3'-to-5' DNA helicase involved in the RecF pathway of recombination . [More information is available at EcoCyc: EG10426].

Gene sequence:
[Download sequence]

Proteins coded by this gene:

Authors Title Journal
Lohman TM Escherichia coli DNA helicases: mechanisms of DNA unwinding. Mol Microbiol Feb. 1, 1992
Mendonca VM, Kaiser-Rogers K, Matson SW Double helicase II (uvrD)-helicase IV (helD) deletion mutants are defective in the recombination pathways of Escherichia coli. J Bacteriol Aug. 1, 1993
Mendonca VM, Klepin HD, Matson SW DNA helicases in recombination and repair: construction of a delta uvrD delta helD delta recQ mutant deficient in recombination and repair. J Bacteriol March 1, 1995
Lovett ST, Sutera VA Jr Suppression of recJ exonuclease mutants of Escherichia coli by alterations in DNA helicases II (uvrD) and IV (helD). Genetics May 1, 1995
Mendonca VM, Matson SW Genetic analysis of delta helD and delta uvrD mutations in combination with other genes in the RecF recombination pathway in Escherichia coli: suppression of a ruvB mutation by a uvrD deletion. Genetics Oct. 1, 1995

Last modification of this entry: Oct. 6, 2010.

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