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HelD |
Protein FULL name:
helicase IV [Escherichia coli].
HelD (Escherichia coli strain K-12 substr. MG1655) is product of expression of helD gene.
FUNCTION: Helicase IV catalyzes the unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand in a reaction that is dependent upon the hydrolysis of ATP.
CATALYTIC ACTIVITY: ATP + H(2)O = ADP + phosphate.
INTERACTION: P37095:pepB; NbExp=1; IntAct=EBI-551473, EBI-549539; P0A6N1:tufA; NbExp=1; IntAct=EBI-551473, EBI-301077;
SIMILARITY: Belongs to the helicase family. UvrD subfamily.
SIMILARITY: Contains 1 uvrD-like helicase ATP-binding domain.
| NCBI GenPept GI number(s): |
146328 |
| Species: | Escherichia coli |
Links to other databases:
| Database | ID | Link |
| Uniprot | P15038 |
P15038 |
| PFAM: | - |
P15038 (Link - using uniprot id) |
| InterPro: | - |
P15038 (Link - using uniprot id) |
| CATH: | - | - |
| SCOP: | - | - |
| PDB: | - | - |
Protein sequence:
|
MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLLAIHCKR GLVWGELEFVLPDEKVVRLPGTEWGETQRFYHHLDAHWRRWSGEMSEIAS GVLRQQLDLIATRTGENKWLTREQTSGVQQQIRQALLRVALPVNRLEEFD NCREAWRKCQAWLKDIESARLQHNQAYTEAMLTEYADFFRQVESSPLNPA QARAVVNGEHSLLVLAGAGSGKTSVLVARAGWLLARGEASPEQILLLAFG RKAAEEMDERIRERLHTEDITARTFHALALHIIQQGSKKVPIVSKLENDT AARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQWSVPEGNFWDDEKLQR RLASRLDRWVSLMRIDGGAQAEMIASAPEEIRDLFSKRIKLMAPLLKAWK GALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGERCDLDT TYRFNSRIGEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDESQLDALL DKLSGYAKPEERILILARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQ QADYVIIVGLQEGSDGFPAAARESIMEEALLPPVEDFPDAEERRLMYVAL TRARHRVWALFNKENPSPFVEILKNLDVPVARKP |
References:
| Title | Authors | Journal |
| The molecular cloning of the gene encoding the Escherichia coli 75-kDa helicase and the determination of its nucleotide sequence and gentic map position. | Wood ER, Matson SW | J Biol Chem May 15, 1989 |
| A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map. | Oshima T, Aiba H, Baba T, Fujita K, Hayashi K, Honjo A, Ikemoto K, Inada T, Itoh T, Kajihara M, Kanai K, Kashimoto K, Kimura S, Kitagawa M, Makino K, Masuda S, Miki T, Mizobuchi K, Mori H, Motomura K, Nakamura Y, Nashimoto H, Nishio Y, Saito N, Horiuchi T, et al. | DNA Res June 1, 1996 |
| The complete genome sequence of Escherichia coli K-12. | Blattner FR, Plunkett G 3rd, Bloch CA, Perna NT, Burland V, Riley M, Collado-Vides J, Glasner JD, Rode CK, Mayhew GF, Gregor J, Davis NW, Kirkpatrick HA, Goeden MA, Rose DJ, Mau B, Shao Y | Science Sept. 5, 1997 |
| Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. | Hayashi K, Morooka N, Yamamoto Y, Fujita K, Isono K, Choi S, Ohtsubo E, Baba T, Wanner BL, Mori H, Horiuchi T | Mol Syst Biol Jan. 1, 2006 |
Last modification of this entry: Oct. 6, 2010.
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