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topA
Unnamed Gene ID: 945862
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Known also as: asuA?; ECK1268; JW1266; supX;
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Topoisomerase I is a type IA topoisomerase which is responsible for relaxing negative supercoils in DNA. [More information is available at EcoCyc: EG11013].
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Gene sequence:
Proteins coded by this gene:
References:
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Authors
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Title
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Journal
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Tse-Dinh YC
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Zinc (II) coordination in Escherichia coli DNA topoisomerase I is required for cleavable complex formation with DNA.
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J Biol Chem
Aug. 5, 1991
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Drlica K
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Control of bacterial DNA supercoiling.
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Mol Microbiol
Jan. 1, 1992
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Oram M, Fisher LM
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An Escherichia coli DNA topoisomerase I mutant has a compensatory mutation that alters two residues between functional domains of the DNA gyrase A protein.
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J Bacteriol
June 1, 1992
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Ishii S, Murakami T, Shishido K
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A pSC101-par sequence-mediated study on the intracellular state of supercoiling of the pBR322 genome in Escherichia coli DNA topoisomerase I deletion mutant.
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FEMS Microbiol Lett
June 1, 1992
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Mizushima T, Natori S, Sekimizu K
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Inhibition of Escherichia coli DNA topoisomerase I activity by phospholipids.
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Biochem J
July 15, 1992
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Last modification of this entry: Oct. 6, 2010.
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