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MMR: MutSalpha interacts with MutLalpha on heteroduplex DNA with nick 5' to mismatch
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GO molecular function: 0005515 |
After recognizing the error in DNA, ATP-bound MutS physically interacts with the MutL protein, which then activates a chain of events leading to the repair of the error. |
![]() | Mismatch in heteroduplex DNA with nick 5' to mismatch bound by MutSalpha in Homo sapiens |
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![]() | Mismatch in heteroduplex DNA with nick 5' to mismatch bound by MutSalpha-MutLalpha complex in Homo sapiens |
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