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base mismatch(base mismatch) |
| Mismatches appear when two nucleobases, which normally do not form a basepair, appear in opposite strands at the same position in a DNA helix - For example pairs GT or AC. |
Sources:
Effects:
Recognizing proteins:
| Protein | Species |
| MLH1 | Homo sapiens |
| MSH2 | Homo sapiens |
| MSH6 | Homo sapiens |
| Msh2p | Saccharomyces cerevisiae |
| Msh3p | Saccharomyces cerevisiae |
| MutH | Escherichia coli |
| MutL | Escherichia coli |
| MutS | Escherichia coli |
| SMUG1 | Homo sapiens |
| TDG | Homo sapiens |
Species:
Is connected with following human diseases:
References:
| Authors | Title | Journal |
| Kunz C, Saito Y, Schar P | DNA Repair in mammalian cells: Mismatched repair: variations on a theme. |
|
| Cline SD, Hanawalt PC | Who's on first in the cellular response to DNA damage? | Nat Rev Mol Cell Biol. May 4, 2004 |
Keywords:
Last modification of this entry: Nov. 11, 2010.
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