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"The RAD2 gene of Saccharomyces cerevisiae: nucleotide sequence and transcript mapping."

Nicolet CM, Chenevert JM, Friedberg EC



Published Jan. 1, 1985 in Gene volume 36 .

Pubmed ID: 3000874

Abstract:
We have determined the nucleotide (nt) sequence of a segment of the yeast chromosome carrying the RAD2 gene. The coding region consists of 2925 bp and could encode a protein of 975 amino acids with a calculated Mr of 111 100. A major transcriptional start point was mapped to a position of approx. 22 bp upstream from the first ATG codon. A number of minor transcriptional start points were also identified in this region, all of them 5' to the putative translational start codon. We noted a number of consensus nt sequences in the 5' and 3' non-coding regions of the RAD2, RAD1 and RAD3 genes of Saccharomyces cerevisiae. In addition, three regions of amino acid sequence homology in the putative RAD1 and RAD2 polypeptides were observed.


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Last modification of this entry: Oct. 6, 2010

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