REPAIRtoire - a database of DNA repair pathways
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First author
Title
PubMed ID
Groth A
Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint.
12660173
Interthal H
Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages.
16141202
Anderson CW
Human TP53 from the malignant glioma-derived cell lines M059J and M059K has a cancer-associated mutation in exon 8.
11023613
Demuth I
Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation.
15467758
Hazrati A
Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.
18006388
Fekairi S
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases.
19596236
Motegi A
Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination.
17130289
Unk I
Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigen.
17108083
Shimamoto A
Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta.
10710432
Tanaka K
Human Rad54B is a double-stranded DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54.
11884632
de Jager M
Human Rad50/Mre11 is a flexible complex that can tether DNA ends.
11741547
Dolganov GM
Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair.
8756642
Cheong JH
Human RPB5, a subunit shared by eukaryotic nuclear RNA polymerases, binds human hepatitis B virus X protein and may play a role in X transactivation.
7828586
Shpakovskii DG
Human PMS2 gene family: origin, molecular evolution, and biological implications.
16913423
Takao M
Human Nei-like protein NEIL3 has AP lyase activity specific for single-stranded DNA and confers oxidative stress resistance in Escherichia coli mutant.
19170771
Oyama M
Human NTH1 physically interacts with p53 and proliferating cell nuclear antigen.
15358233
Gu Y
Human MutY homolog, a DNA glycosylase involved in base excision repair, physically and functionally interacts with mismatch repair proteins human MutS homolog 2/human MutS homolog 6.
11801590
Chen XB
Human Mus81-associated endonuclease cleaves Holliday junctions in vitro.
11741546
Nomura Y
Human Mus81 and FANCB independently contribute to repair of DNA damage during replication.
17903171
Unk I
Human HLTF functions as a ubiquitin ligase for proliferating cell nuclear antigen polyubiquitination.
18316726
Nakanishi K
Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair.
15650050
MacInnes MA
Human ERCC5 cDNA-cosmid complementation for excision repair and bipartite amino acid domains conserved with RAD proteins of Saccharomyces cerevisiae and Schizosaccharomyces pombe.
8413238
Wertz IE
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase.
14739464
Zheng L
Human DNA2 is a mitochondrial nuclease/helicase for efficient processing of DNA replication and repair intermediates.
18995831
Poltoratsky VP
Human DNA-activated protein kinase (DNA-PK) is homologous to phosphatidylinositol kinases.
7594449
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