|
Wrn
Werner syndrome homolog (human)
|
|
On chromosome: 8 20.0 cM
Known also as: AI846146;
Mus musculus Werner syndrome homolog (human) (Wrn), transcript variant 1.
|
Gene sequence:
Proteins coded by this gene:
References:
Authors
|
Title
|
Journal
|
Lebel M, Leder P
|
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity.
|
Proc Natl Acad Sci U S A
Oct. 27, 1998
|
Huang S, Beresten S, Li B, Oshima J, Ellis NA, Campisi J
|
Characterization of the human and mouse WRN 3'-->5' exonuclease.
|
Nucleic Acids Res
June 15, 2000
|
Kawabe Yi, Branzei D, Hayashi T, Suzuki H, Masuko T, Onoda F, Heo SJ, Ikeda H, Shimamoto A, Furuichi Y, Seki M, Enomoto T
|
A novel protein interacts with the Werner's syndrome gene product physically and functionally.
|
J Biol Chem
June 8, 2001
|
Lebel M, Lavoie J, Gaudreault I, Bronsard M, Drouin R
|
Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice.
|
Am J Pathol
May 1, 2003
|
Chang S, Multani AS, Cabrera NG, Naylor ML, Laud P, Lombard D, Pathak S, Guarente L, DePinho RA
|
Essential role of limiting telomeres in the pathogenesis of Werner syndrome.
|
Nat Genet
Aug. 1, 2004
|
Last modification of this entry: Oct. 6, 2010.
Add your own comment!
There is no comment yet.
|