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3mA

(3-methyl-2'-deoxyadenosine-5'-monophosphate)



Smiles represantation:
[H]O[C@@]1([H])C([H])([H])[C@@]([H])(O[C@]1([H])C([H])([H])OP(O)(O)=O)n1c([H])nc2c1[N](=C([H])N=C2N([H])[H])C([H])([H])[H]


Occurs frequently. Repaired by direct repair (DR) mechanisms. AlkB activity not confirmed. Also repaired by the BER pathway.


Download [.mol file for 3mA]

Sources:

Effects:

Recognizing proteins:
Protein Species
AlkA Escherichia coli
MPG Homo sapiens
Mag1p Saccharomyces cerevisiae
Tag Escherichia coli


Species:

References:

Authors Title Journal
Mishina Y, He C Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins.
-
Sancar A, Lindsey-Boltz LA, Unsal-KaƧmaz K, Linn S Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem. Jan. 1, 2004

Keywords:

Last modification of this entry: Oct. 22, 2010.

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