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Bujnicki Lab Homepage

Analysis for Plasmodium falciparum



In living organisms there are lots of DNA repair pathways, including DDS, DRR, BER, NER, MMR, HRR, NHEJ, TLS. For a reference pathway we have choosen MMR, because it has a good quality annotated orthologic proteins for referenced organisms; we have choosen a human, yeast and E.coli, which are described in REPAIRtoire database.

Using inParanoid database we created a table for those organisms

Numbers in cells represent common ortholog proteins from MMR pathway found in given organism in each row and simultaneously present in the one in the current column.

Orthologs

H. sapiens

S. cerevisiae

E. coli

H. sapiens 23 18 3
S. cerevisiae 18 20 3
E. coli 3 2 21
P. falciparum 14 13 2

Number of proteins (for example yeast [rows] -> human [columns]) was calculated by fetching all proteins from MMR pathway from KEGG database for those yeast. Using inParanoid database we fetched all orthologs for those proteins in human. It's good to know that P. falciparum has 18 proteins involved in MMR pathway.


In table below, we placed all P. falciparum proteins involved in one of the DNA repair pathways (described above) and that have at least one results from algorithm (structure or sequence search result) and with e-value threshold equals e^-50:


Uniprot Full name Putative EC number Gen Function Sequence only E-value Sequence, structure E-value
Q8IAN4 DNA repair protein rad54 yes PF08_0126
  • Complete proteome
  • Reference proteome
Q92698 4e-96 Q92698 6.3e-96
Q8I4W3 Rac-beta serine/threonine protein kinase yes PFL2250c
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Serine/threonine-protein kinase
  • Transferase
O14757 5.6e-56
Q8ID74 Polynucleotide kinase yes PF13_0334
  • Complete proteome
  • Kinase
  • Reference proteome
  • Transferase
Q96T60 3e-65
C6KSQ1 Serine/threonine protein kinase, Pfnek-5 no PFF0260w
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Serine/threonine-protein kinase
  • Transferase
O14757 5.2e-51
Q8I3V5 Phosphatidylinositol 3-kinase yes 2.7.1.137 PFE0765w
  • Complete proteome
  • Kinase
  • Reference proteome
  • Transferase
P38111 2.5e-54
Q8IM12 DNA-repair helicase yes PF14_0081
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Nucleus
  • Reference proteome
P06839 1.3e-82 P06839 5.2e-96
Q7KQL4 no PF10_0165
  • Complete proteome
  • DNA replication
  • DNA-binding
  • DNA-directed DNA polymerase
  • Nucleotidyltransferase
  • Reference proteome
  • Transferase
P15436 2e-206 P28340 2e-213
C6KSP4 DNA helicase yes PFF0225w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
Q92698 3.1e-62
Q8ID59 DNA-directed RNA polymerase 2 yes 2.7.7.6 PF13_0341
  • Complete proteome
  • DNA-directed RNA polymerase
  • Nucleotidyltransferase
  • Reference proteome
  • Transcription
  • Transferase
P19388 2.9e-62 P19388 2.7e-83
C0H4L8 DNA mismatch repair protein yes MAL7P1.206
  • Complete proteome
  • Reference proteome
P25847 4.6e-79 P25847 1e-100
Q8I3W6 Helicase, belonging to UvrD family yes PFE0705c
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P03018 1.4e-74
Q8IIJ0 DNA mismatch repair protein MLH1 yes PF11_0184
  • Complete proteome
  • Reference proteome
P40692 7e-104 P40692 6e-151
Q8IBS5 no CPK4
  • 3D-structure
  • ATP-binding
  • Calcium
  • Complete proteome
  • Developmental protein
  • Differentiation
  • Kinase
  • Lipoprotein
  • Metal-binding
  • Myristate
  • Nucleotide-binding
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Serine/threonine-protein kinase
  • Transferase
O96017 2.8e-56 O96017 2.3e-51
C6KT89 DNA polymerase 1 yes 2.7.7.7 PFF1225c
  • Complete proteome
  • Nucleotidyltransferase
  • Reference proteome
  • Transferase
P00582 3.8e-90
Q8I2U3 Ubiquitin conjugating enzyme yes 6.3.2.19 PFI1030c
  • Complete proteome
  • Ligase
  • Reference proteome
  • Ubl conjugation pathway
P52490 8.7e-51
C6S3D8 Topoisomerase yes PF10_0412
  • Complete proteome
  • Isomerase
  • Reference proteome
P23179 1.3e-67
O77380 CPSF (Cleavage and polyadenylation specific factor), subunit A yes PFC0780w
  • Complete proteome
  • Reference proteome
Q16531 1.9e-94
Q8IAU5 Cullin-like protein yes PF08_0094
  • Complete proteome
  • Reference proteome
Q13619 4.6e-71 Q13619 2e-124
Q8IJ38 no PF10_0362
  • Complete proteome
  • DNA replication
  • DNA-binding
  • DNA-directed DNA polymerase
  • Nucleotidyltransferase
  • Reference proteome
  • Transferase
P14284 7.3e-66 P14284 4e-167
Q8IFP1 U5 small nuclear ribonucleoprotein-specific protein yes PFD1060w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
  • Ribonucleoprotein
  • Viral nucleoprotein
  • Virion
O75417 8.9e-62
Q8I607 Ubiquitin conjugating enzyme E2 yes 6.3.2.19 PFL0190w
  • Complete proteome
  • Ligase
  • Reference proteome
  • Ubl conjugation pathway
P52490 2e-52
Q8IKK3 DNA polymerase alpha subunit yes PF14_0602
  • Complete proteome
  • Reference proteome
P24482 3.6e-56
O96136 ERCC1 nucleotide excision repair protein yes PFB0160w
  • Complete proteome
  • Reference proteome
P07992 5.1e-59
Q8I574 Splicing factor 3b, subunit 3, 130kD yes PFL1680w
  • Complete proteome
  • Reference proteome
Q16531 2e-111 Q16531 9e-145
Q8I4S6 DNA repair protein rhp16 yes PFL2440w
  • Complete proteome
  • Reference proteome
P32863 1.8e-54 P32863 1.8e-61
Q9NJU9 no CPK3
  • 3D-structure
  • ATP-binding
  • Calcium
  • Complete proteome
  • Developmental protein
  • Differentiation
  • Kinase
  • Metal-binding
  • Nucleotide-binding
  • Reference proteome
  • Repeat
  • Serine/threonine-protein kinase
  • Transferase
O96017 7.9e-57
Q7K6A0 cAMP-dependent protein kinase catalytic subunit no PfPKAc
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Serine/threonine-protein kinase
  • Transferase
O14757 4.1e-52
C6KTD8 DNA polymerase epsilon, catalytic subunit a yes 2.7.7.7 PFF1470c
  • Complete proteome
  • Nucleotidyltransferase
  • Reference proteome
  • Transferase
P21951 6e-208 Q07864 0.0
Q9U0H1 no PFD0590c
  • Complete proteome
  • DNA replication
  • DNA-binding
  • DNA-directed DNA polymerase
  • Nucleotidyltransferase
  • Reference proteome
  • Transferase
P15436 6.2e-79 P15436 7e-149
Q8IBK1 Exonuclease I yes PF07_0105
  • Complete proteome
  • Exonuclease
  • Hydrolase
  • Nuclease
  • Reference proteome
P39875 2.6e-65
Q8I1X9 ATP-dependent RNA Helicase yes 3.6.1.3 PFD0245c
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P46063 1e-53
Q9U0J0 Replication factor a protein yes PFD0470c
  • Complete proteome
  • Reference proteome
P27694 4.1e-56 P27694 8.2e-80
Q8IKG6 DNA-3-methyladenine glycosylase yes PF14_0639
  • Complete proteome
  • Reference proteome
P29372 2.7e-63
Q8ILY1 Pfprex no POM1
  • Complete proteome
  • Reference proteome
P00582 5.1e-63 P00582 1.2e-94
O97290 ATP-dependent RNA Helicase yes PFC0955w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P35187 9.3e-52
Q8I1Q9 Cdc2-related protein kinase 1 no Pfcrk-1
  • Complete proteome
  • Kinase
  • Reference proteome
  • Transferase
P50613 6.2e-51
Q8ILI9 DNA mismatch repair protein Msh2p yes PF14_0254
  • Complete proteome
  • Reference proteome
P25847 1.2e-83 P25847 1e-102
Q8I416 ATP-dependent RNA Helicase yes PFE0430w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P35187 1.6e-51
Q8IJN8 Ribonucleotide reductase small subunit yes PF10_0154
  • Complete proteome
  • Reference proteome
P49723 8.5e-83
Q8I5R8 RNA polymerase subunit 8c yes PFL0665c
  • Complete proteome
  • Reference proteome
P52434 1.9e-65
Q8IBN8 DEAD box helicase yes MAL7P1.113
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
  • RNA-binding
P35187 8.5e-51
Q8IJW1 Endonuclease yes PF10_0080
  • Complete proteome
  • Endonuclease
  • Hydrolase
  • Nuclease
  • Reference proteome
P39748 5.8e-57
Q8IDV5 Calcium-dependent protein kinase yes 2.7.11.17 PF13_0211
  • ATP-binding
  • Calcium
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Transferase
O96017 1.1e-58
Q8IKF0 Helicase 45 no H45
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 5e-60
Q8IJS8 DNA repair protein RAD23 yes PF10_0114
  • Complete proteome
  • Reference proteome
P54727 1.2e-77
Q8IFN9 Eukaryotic initiation factor yes PFD1070w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Initiation factor
  • Nucleotide-binding
  • Protein biosynthesis
  • Reference proteome
O94762 7e-57
Q8IL78 DEAD/DEAH box helicase yes PF14_0370
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O75417 8.5e-58
O77321 DNA polymerase epsilon subunit B yes PFC0340w
  • Complete proteome
  • Reference proteome
P46957 8.2e-64 P46957 1e-115
C6KSY9 Endonuclease III homologue yes 4.2.99.18 PFF0715c
  • Complete proteome
  • Endonuclease
  • Hydrolase
  • Lyase
  • Nuclease
  • Reference proteome
P78549 2.1e-53
Q8IB05 Meiotic recombination protein dmc1-like protein no MAL8P1.76
  • ATP-binding
  • Complete proteome
  • Nucleotide-binding
  • Reference proteome
P25454 1.3e-67 P25454 1e-58
Q8IDG5 Uncharacterized protein no PF13_0279
  • Complete proteome
  • Reference proteome
Q12004 6.9e-72
Q8IJ90 Uncharacterized protein no PF10_0309
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 6.6e-52
C0H4G2 Serine/threonine-protein kinase Nek-2 no 2.7.1.- Pfnek-2
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Transferase
O14757 2.7e-51 O14757 4.2e-51
Q8IKX5 Serine/threonine protein kinase yes PF14_0476
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Serine/threonine-protein kinase
  • Transferase
O14757 1.6e-51
Q8IDD0 DNA helicase yes PF13_0308
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
Q92698 1.1e-66
Q8IEG6 TFIIH basal transcription factor subunit no Ssl-like protein
  • Complete proteome
  • Metal-binding
  • Reference proteome
  • Zinc
  • Zinc-finger
Q04673 5.8e-70 Q13888 2e-108
C6S3H8 RNA helicase yes PF14_0183b
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P46063 6e-52
Q8I3J4 Ubiquitin conjugating enzyme yes PFE1350c
  • 3D-structure
  • Complete proteome
  • Ligase
  • Reference proteome
  • Ubl conjugation pathway
P52490 2.3e-53
Q8I511 DEAD/DEAH box helicase yes PFL2010c
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P35187 1.4e-52
Q7KQJ9 no PFL1285c
  • Complete proteome
  • DNA replication
  • DNA-binding
  • Nucleus
  • Reference proteome
P15873 4.9e-51
C6KSR0 Ubiquitin conjugating enzyme E2 yes PFF0305c
  • Complete proteome
  • Reference proteome
P52490 9.1e-51
Q8ILG5 ATP-dependent DNA helicase yes PF14_0278
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P15043 2.7e-74 P15043 4.3e-80
C6KTE4 DEAD/DEAH box ATP-dependent RNA helicase yes PFF1500c
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
  • RNA-binding
O94762 5.6e-52 P35187 3.6e-52
Q8I4Y8 Uncharacterized protein no PFL2125c
  • Complete proteome
  • Reference proteome
Q02939 1e-126
Q8I3Y3 CDK-activating kinase assembly factor yes PFE0610c
  • Complete proteome
  • Kinase
  • Metal-binding
  • Reference proteome
  • Transferase
  • Zinc
  • Zinc-finger
Q03290 7.6e-55
Q8I2H7 DNA excision-repair helicase yes PFI1650w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Nucleus
  • Reference proteome
P06839 9e-131 P06839 3e-125
Q8I347 Uncharacterized protein yes PFI0510c
  • Complete proteome
  • Reference proteome
Q9UBZ9 4.2e-89
Q8IJG6 Uncharacterized protein no PF10_0232
  • Complete proteome
  • Nucleus
  • Reference proteome
Q92698 3.1e-70 Q92698 1.7e-70
Q8ILL6 Calcium/calmodulin-dependent protein kinase yes PF14_0227
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Transferase
O96017 7.3e-59 O96017 2.3e-51
Q8I3I8 RNA helicase-1 no PFE1390w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 4.5e-60
Q8I0W7 Snrnp protein yes PFE0925c
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 1.7e-54
Q8II71 26S proteasome regulatory complex subunit yes PF11_0303
  • Complete proteome
  • Proteasome
  • Reference proteome
Q13098 1e-51 Q13098 6.8e-72
Q8IDW1 Protein kinase 6 no 2.7.11.17 PfPK6
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Transferase
P50613 1.1e-51
O97285 ATP-dependent RNA Helicase yes 3.6.1.3 PFC0915w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 1.8e-52 P46063 5.7e-52
C6KTD3 Cullin-like protein yes PFF1445c
  • Complete proteome
  • Reference proteome
Q13619 2.9e-96
Q8ILU6 no PF14_0148
  • Complete proteome
  • DNA damage
  • DNA repair
  • Glycosidase
  • Hydrolase
  • Mitochondrion
  • Nucleus
  • Reference proteome
P12295 1e-69 P13051 7.7e-87
O96139 5'-3' exonuclease, N-terminal resolvase-like domain yes PFB0180w
  • Complete proteome
  • Exonuclease
  • Hydrolase
  • Nuclease
  • Reference proteome
P00582 6.2e-65
Q8I0W8 Deoxyribodipyrimidine photolyase (Photoreactivating enzyme, DNA photolyase) yes 4.1.99.3 PFE0675c
  • Complete proteome
  • Lyase
  • Reference proteome
P05066 6.1e-92
Q8IKK0 Cyclin homologue no cyc-1
  • Complete proteome
  • Cyclin
  • Reference proteome
P37366 5.9e-57
Q8I5N7 Conserved Plasmodium protein no PFL0825c
  • Complete proteome
  • Reference proteome
P23179 1.1e-65
Q8IAU1 RNA helicase yes PF08_0096
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 2.8e-55
Q8ILK9 DNA-directed DNA polymerase yes PF14_0234
  • ATP-binding
  • Complete proteome
  • DNA-directed DNA polymerase
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Nucleotidyltransferase
  • Reference proteome
  • Transferase
O75417 1.8e-81
O96264 DEAD/DEAH box helicase yes PFB0860c
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 9.8e-54
Q8I5E7 ATP-dependent RNA helicase yes PFL1310c
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 3.5e-59
Q8IL13 Helicase yes PF14_0437
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 2.4e-60 O94762 6.9e-51
Q8I447 no PFE0270c
  • ATP-binding
  • Complete proteome
  • DNA damage
  • DNA repair
  • DNA-binding
  • Nucleotide-binding
  • Reference proteome
P52701 3e-123 Q03834 2e-150
Q7K734 no FEN1
  • Complete proteome
  • DNA damage
  • DNA repair
  • DNA replication
  • Endonuclease
  • Exonuclease
  • Hydrolase
  • Magnesium
  • Metal-binding
  • Mitochondrion
  • Nuclease
  • Nucleus
  • Phosphoprotein
  • Reference proteome
P39748 7.2e-75 P39748 2.7e-75
Q8I579 Uncharacterized protein no PFL1655c
  • Complete proteome
  • Reference proteome
P24482 2.7e-98
O96154 DNA repair endonuclease yes PFB0265c
  • Complete proteome
  • Endonuclease
  • Hydrolase
  • Nuclease
  • Nucleus
  • Reference proteome
P28715 4.2e-74
Q8IES4 no PfLigI
  • ATP-binding
  • Complete proteome
  • DNA damage
  • DNA recombination
  • DNA repair
  • DNA replication
  • Ligase
  • Nucleotide-binding
  • Reference proteome
P18858 9e-115 P18858 3e-138
Q8IKY1 DNA replication related protein yes PF14_0470
  • Complete proteome
  • Reference proteome
Q96NY9 2.7e-56
Q8IDQ5 DNA helicase yes MAL13P1.216
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Metal-binding
  • Nucleotide-binding
  • Reference proteome
  • Zinc
  • Zinc-finger
P32863 4.2e-52 Q9Y620 1.1e-68
Q8IM38 Ribonucleotide reductase small subunit no PF14_0053
  • Complete proteome
  • Reference proteome
P49723 2.1e-72 P49723 1.1e-84
C0H4V8 DNA helicase yes MAL8P1.65
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P32863 2e-53 Q03468 1.5e-69
P61075 no CRK2
  • ATP-binding
  • Complete proteome
  • Cytoplasm
  • Kinase
  • Nucleotide-binding
  • Phosphoprotein
  • Reference proteome
  • Serine/threonine-protein kinase
  • Transferase
P50613 5.5e-62 P50613 1.5e-53
Q8IBJ3 Mismatch repair protein pms1 homologue yes MAL7P1.145
  • Complete proteome
  • Reference proteome
P54278 6.1e-71 P14242 4.4e-98
Q8I301 Ubiquitin conjugating enzyme yes PFI0740c
  • 3D-structure
  • Complete proteome
  • Ligase
  • Reference proteome
  • Ubl conjugation pathway
P52490 4.3e-51
Q8I4R9 DEAD/DEAH box helicase yes PFL2475w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 9.9e-52 P35187 5.3e-53
Q8I534 Calcium/calmodulin-dependent protein kinase 2 yes PFL1885c
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Transferase
O96017 2e-52
Q8I3A1 Replication factor A-related protein yes PFI0235w
  • Complete proteome
  • Reference proteome
P27694 8.3e-84
Q8IKT6 Serine/threonine protein kinase yes KIN
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Serine/threonine-protein kinase
  • Transferase
O14757 1.7e-51
Q8IIS8 Rad51 homolog no Rad51
  • ATP-binding
  • Complete proteome
  • Nucleotide-binding
  • Reference proteome
P25454 1.2e-72 P25454 6.2e-62
Q8IDM7 DNA topoisomerase III yes 5.99.1.2 PF13_0251
  • Complete proteome
  • Isomerase
  • Reference proteome
P06612 4e-69 P06612 6e-128
O96271 Replication factor C subunit 1 yes PFB0895c
  • Complete proteome
  • Reference proteome
P35251 3e-83 P35251 2e-102
C6KT82 Smarca-related protein no PFF1185w
  • Complete proteome
  • Metal-binding
  • Reference proteome
  • Zinc
  • Zinc-finger
Q92698 2.9e-57 Q92698 1.7e-66
Q8ID22 DNA repair endonuclease yes MAL13P1.346
  • Complete proteome
  • Endonuclease
  • Hydrolase
  • Nuclease
  • Reference proteome
P06777 1e-117
P62344 no CPK1
  • ATP-binding
  • Calcium
  • Complete proteome
  • Kinase
  • Lipoprotein
  • Membrane
  • Metal-binding
  • Myristate
  • Nucleotide-binding
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Serine/threonine-protein kinase
  • Transferase
O96017 4e-57 O96017 7.2e-51
Q8IAW2 Ubiquitin conjugating enzyme yes PF08_0085
  • Complete proteome
  • Ligase
  • Reference proteome
  • Ubl conjugation pathway
P52490 1e-51
Q8IE72 DEAD box helicase yes MAL13P1.134
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P06839 6.2e-94
C0H4N8 Protein kinase no Pfnek-4
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Transferase
O14757 6e-53
P61074 no PCNA
  • Complete proteome
  • DNA replication
  • DNA-binding
  • Nucleus
  • Reference proteome
P15873 1.8e-53
Q8IJQ1 Cdk7 yes PF10_0141
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Transferase
P50613 1.2e-53
Q8IIW0 PfSNF2L no PF11_0053
  • Complete proteome
  • Reference proteome
Q92698 5e-81 P40352 8.5e-80
Q8I2W7 DNA helicase yes PFI0910w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P15043 6.2e-64 P15043 6.7e-61
Q8I2Y2 N-glycosylase/DNA lyase yes 3.2.2.- PFI0835c
  • Complete proteome
  • Glycosidase
  • Hydrolase
  • Lyase
  • Reference proteome
O15527 9e-62
O96239 DEAD/DEAH box helicase yes PFB0730w
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
Q92698 2.2e-65 Q92698 5.9e-74
Q8IE01 ATP-dependent RNA Helicase yes PF13_0177
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P46063 3.3e-52
Q8IEG4 Serine/threonine protein kinase no 2.7.1.- PfPK9
  • ATP-binding
  • Complete proteome
  • Kinase
  • Nucleotide-binding
  • Reference proteome
  • Serine/threonine-protein kinase
  • Transferase
O14757 1e-53 O96017 3.6e-51
Q8IJ31 DNA repair helicase rad25 yes PF10_0369
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
P19447 4e-111 P19447 2e-127
Q8ICR0 no CPK2
  • ATP-binding
  • Calcium
  • Complete proteome
  • Kinase
  • Lipoprotein
  • Metal-binding
  • Myristate
  • Nucleotide-binding
  • Reference proteome
  • Repeat
  • Serine/threonine-protein kinase
  • Transferase
O96017 5.2e-63
Q8IBY6 Nucleotide excision repair protein yes MAL7P1.32
  • Complete proteome
  • Reference proteome
P23025 5.9e-69
Q8II68 A/G-specific adenine glycosylase yes PF11_0306
  • Complete proteome
  • Reference proteome
Q9UIF7 1.5e-72
Q9TY94 DEAD box helicase, UAP56 no UAP56
  • ATP-binding
  • Complete proteome
  • Helicase
  • Hydrolase
  • Nucleotide-binding
  • Reference proteome
O94762 1.9e-53
O77397 Ubiquitin conjugating enzyme yes PFC0855w
  • Complete proteome
  • Ligase
  • Reference proteome
  • Ubl conjugation pathway
P52490 5.8e-52
C0H4W3 no PF08_0048
  • ATP-binding
  • Chromatin regulator
  • Coiled coil
  • Complete proteome
  • DNA-binding
  • Helicase
  • Hydrolase
  • Merozoite
  • Nucleotide-binding
  • Nucleus
  • Reference proteome
  • Transcription
  • Transcription regulation
Q92698 7.5e-63 Q03468 6.5e-63
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