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strand break with 3'OH

(single strand break between 5'P and 3'OH)





This single strand break occurs when the bond between the phosphorus atom and the 3'OH is broken. The phosphate group remains on the 3' side of the broken strand, while the 5' part of the strand has an alcoholic OH group.



Recognizing proteins:
Protein Species
APEX1 Homo sapiens
APEX2 Homo sapiens
APTX Homo sapiens
ATM Homo sapiens
Apn2p Saccharomyces cerevisiae
BLM Homo sapiens
BRCA1 Homo sapiens
BRCA2 Homo sapiens
CCNH Homo sapiens
CDK7 (CDKs) Homo sapiens
CHEK1 (CHK1) Homo sapiens
CHEK2 (CHK2) Homo sapiens
DCLRE1A Homo sapiens
DCLRE1B Homo sapiens
Dpb3p Saccharomyces cerevisiae
Dpb4p Saccharomyces cerevisiae
EME1 Homo sapiens
EME2 Homo sapiens
ERCC1 Homo sapiens
FANCB Homo sapiens
FANCC Homo sapiens
FANCE Homo sapiens
FANCM Homo sapiens
HUS1 Homo sapiens
LIG4 Homo sapiens
MDC1 Homo sapiens
MRE11A Homo sapiens
NBN (NBS1) Homo sapiens
PARP1 Homo sapiens
PARP2 Homo sapiens
PCNA Homo sapiens
POLB Homo sapiens
POLD1 Homo sapiens
POLE Homo sapiens
POLG Homo sapiens
POLL Homo sapiens
POLM Homo sapiens
POLN Homo sapiens
POLQ Homo sapiens
Pol epsilon Saccharomyces cerevisiae
Pol30p Saccharomyces cerevisiae
Pol32p Saccharomyces cerevisiae
Pol3p Saccharomyces cerevisiae
Pol4p Saccharomyces cerevisiae
PolII Escherichia coli
RAD1 Homo sapiens
RAD17 Homo sapiens
RAD51C Homo sapiens
RAD51L1 Homo sapiens
RAD51L3 Homo sapiens
RAD54B Homo sapiens
RAD54L Homo sapiens
RAD9A Homo sapiens
RBBP8 Homo sapiens
RECQL Homo sapiens
RECQL2 (WRN) Homo sapiens
RECQL4 Homo sapiens
RECQL5 Homo sapiens
RPA1 Homo sapiens
RPA2 Homo sapiens
RPA3 Homo sapiens
RRM2B Homo sapiens
Rpa1p Saccharomyces cerevisiae
SHFM1 Homo sapiens
TP53 Homo sapiens
TREX1 Homo sapiens
TREX2 Homo sapiens
Topoisomerase I (sub omega) Escherichia coli
XRCC1 Homo sapiens
XRCC2 Homo sapiens
XRCC3 Homo sapiens
XRCC4 Homo sapiens
XprB Escherichia coli


Keywords:

Last modification of this entry: July 7, 2011.

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