REPAIRtoire - a database of DNA repair pathways

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Proteins



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Protein name Alternative names Species GenPept GI numbers Uniprot
ALKBH2 alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 [Homo sapiens]. Homo sapiens 48717226
Q6NS38
ALKBH3 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 [Homo sapiens]. Homo sapiens 21040275
Q96Q83
APEX1 DNA-(apurinic or apyrimidinic site) lyase, Apurinic-apyrimidinic endonuclease 1, APEX nuclease, Protein REF-1., Homo sapiens 113984
18375501
P27695
APEX2 DNA-(apurinic or apyrimidinic site) lyase 2, Apurinic-apyrimidinic endonuclease 2, APEX nuclease 2, APEX nuclease-like 2, AP endonuclease XTH2., Homo sapiens 73921676
18375507
Q9UBZ4
APTX aprataxin isoform a [Homo sapiens]. Homo sapiens 28329436
8923156
Q7Z2E3
ATM serine-protein kinase ATM isoform 1 [Homo sapiens]. Homo sapiens 71902540
Q13315
ATR serine/threonine-protein kinase ATR [Homo sapiens]. Homo sapiens 157266317
Q13535
ATRIP ATR-interacting protein isoform 1 [Homo sapiens]. Homo sapiens 18390347
Q8WXE1
Ada Regulatory protein Ada, Regulatory protein of adaptative response, Contains: Methylated-DNA-protein-cysteine methyltransferase, O-6-methylguanine-DNA alkyltransferase., Escherichia coli 461468
P06134
AidB Protein AidB. Escherichia coli 12644215
P33224
AlkA DNA-3-methyladenine glycosylase 2, DNA-3-methyladenine glycosylase II, 3-methyladenine-DNA glycosylase II, inducible, DNA-3-methyladenine glycosidase II., Escherichia coli 112786
P04395
AlkB alkB [Escherichia coli]. Escherichia coli 405945
P05050
Apn1p apurinic/apyrimidinic (AP) lyase 1 Saccharomyces cerevisiae 296146264
P22936
Apn2p apurinic/apyrimidinic (AP) lyase 2 Saccharomyces cerevisiae 6319452
P38207
BLM Bloom syndrome protein, RECQ PROTEIN-LIKE 3; RECQL3; DNA HELICASE, RECQ-LIKE, TYPE 2; RECQ2; BLM GENE; BLM Homo sapiens 4557365
P54132
BRCA1 breast cancer 1, early onset isoform 1 [Homo sapiens]. Homo sapiens 6552301
6552299
P38398
BRCA2 breast cancer type 2 susceptibility protein [Homo sapiens]. Homo sapiens 119395734
P51587
C19ORF40 Fanconi anemia-associated protein of 24 kDa [Homo sapiens]. Homo sapiens 22748623
Q9BTP7
CCNH cyclin-H [Homo sapiens]. Homo sapiens 4502623
P51946
CDK7 (CDKs) Cell division protein kinase 7, CDK-activating kinase, CAK1, TFIIH basal transcription factor complex kinase subunit, 39 kDa protein kinase, p39 Mo15, STK1., Homo sapiens 1705722
4502743
P50613
CDKN1A (p21) Cyclin-dependent kinase inhibitor 1, CDK-interacting protein 1, Melanoma differentiation-associated protein 6, WILDTYPE p53-ACTIVATED FRAGMENT 1 Homo sapiens P38936
CHEK1 (CHK1) serine/threonine-protein kinase Chk1 [Homo sapiens]. Homo sapiens 166295192
O14757
CHEK2 (CHK2) serine/threonine-protein kinase Chk2 isoform a [Homo sapiens]. Homo sapiens 6005850
O96017
COPS5 COP9 signalosome complex subunit 5, Jun activation domain-binding protein 1., Homo sapiens 55976562
Q92905
CSA DNA excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA., Homo sapiens 3121917
4557467
Q13216
CSB DNA excision repair protein ERCC-6, ATP-dependent helicase ERCC6, Cockayne syndrome protein CSB., Homo sapiens 416959
4557565
Q03468
CUL4A Cullin-4A, Homo sapiens 108936013
Q13619
Ccl1p Saccharomyces cerevisiae 6325282
P37366
Cdc9p DNA ligase Saccharomyces cerevisiae 6320038
P04819
DCLRE1A DNA-crosslink repair gene SNM1 [Homo sapiens]. Homo sapiens 42734319
Q6PJP8
DCLRE1B DNA cross-link repair 1B protein [Homo sapiens]. Homo sapiens 12383082
Q9H816
DCLRE1C (Artemis) Protein Artemis, DNA cross-link repair 1C protein, SNM1 homolog C, SNM1-like protein, Protein A-SCID., Homo sapiens 71153325
76496495
Q96SD1
DDB1 DNA damage-binding protein 1, Damage-specific DNA-binding protein 1, UV-damaged DNA-binding factor, DDB p127 subunit, DNA damage-binding protein a, UV-damaged DNA-binding protein 1, Xeroderma pigmentosum group E-complementing protein, XPE-binding factor, HBV X-associated protein 1, Homo sapiens 12643730
148529014
Q16531
DDB2 DNA damage-binding protein 2, Damage-specific DNA-binding protein 2, DDB p48 subunit, UV-damaged DNA-binding protein 2, Homo sapiens 12230033
4557515
Q92466
DNA ligase NAD-dependent DNA ligase [Escherichia coli UTI89]. Escherichia coli 91211748
P15042
Dam DNA adenine methylase [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16131265
P0AEE8
DinB DNA polymerase IV Escherichia coli 16128217
Q47155
DinF DNA-damage-inducible SOS response protein [Escherichia coli str. K-12 substr. W3110]. Escherichia coli 89110765
P28303
DinG ATP-dependent DNA helicase [Escherichia coli str. K-12 substr. W3110]. Escherichia coli 89107650
P27296
DinI DNA damage-inducible protein I [Escherichia coli str. K-12 substr. W3110]. Escherichia coli 89107907
P0ABR1
DinJ predicted antitoxin of YafQ-DinJ toxin-antitoxin system [Escherichia coli str. K-12 substr. W3110]. Escherichia coli 89107101
Q47150
DnaE DNA polymerase III holoenzyme, alpha subunit [Escherichia coli]. Escherichia coli 146663
P10443
DnaN DNA polymerase III beta-subunit [Escherichia coli]. Escherichia coli 145761
P0A988
DnaQ DNA polymerase III epsilon subunit [Escherichia coli]. Escherichia coli 147679
P03007
DnaT DNA biosynthesis protein (primosomal protein I) [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16132183
P0A8J2
DnaX DNA polymerase III subunit tau; Contains: DNA polymerase III subunit gamma. Escherichia coli 118808
P06710
Dnl4p DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth Saccharomyces cerevisiae 6324578
Q08387
Dpb2p DNA polymerase epsilon subunit B, DNA polymerase II subunit 2 Saccharomyces cerevisiae 85681935
P24482
Dpb3p Saccharomyces cerevisiae 429123
P27344
Dpb4p Saccharomyces cerevisiae 6320326
Q04603
EME1 essential meiotic endonuclease 1 homolog 1 [Homo sapiens]. Homo sapiens 22748969
Q96AY2
EME2 probable crossover junction endonuclease EME2 [Homo sapiens]. Homo sapiens 58197552
A4GXA9
ERCC1 DNA excision repair protein ERCC-1 isoform 1 [Homo sapiens]. Homo sapiens 42544169
4503599
119538
P07992
EXO1 exonuclease 1 isoform a [Homo sapiens]. Homo sapiens 39995069
39995071
Q9UQ84
Exo1p 5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains Saccharomyces cerevisiae 6324607
P39875
FANCA Fanconi anemia group A protein isoform a [Homo sapiens]. Homo sapiens 66880553
O15360
FANCB Fanconi anemia group B protein [Homo sapiens]. Homo sapiens 22749293
66528785
Q8NB91
FANCC Fanconi anemia group C protein [Homo sapiens]. Homo sapiens 56118236
Q00597
FANCD2 Fanconi anemia group D2 protein isoform a [Homo sapiens]. Homo sapiens 21361861
Q9BXW9
FANCE Fanconi anemia group E protein [Homo sapiens]. Homo sapiens 11345454
Q9HB96
FANCF Fanconi anemia group F protein [Homo sapiens]. Homo sapiens 12232377
Q9NPI8
FANCG Fanconi anemia group G protein [Homo sapiens]. Homo sapiens 4759336
O15287
FANCI Fanconi anemia group I protein isoform 2 [Homo sapiens]. Homo sapiens 82830440
Q9NVI1
FANCL E3 ubiquitin-protein ligase FANCL isoform 2 [Homo sapiens]. Homo sapiens 49472819
Q9NW38
FANCM Fanconi anemia group M protein [Homo sapiens]. Homo sapiens 74959747
Q8IYD8
FEN1 flap structure-specific endonuclease 1 [Homo sapiens]. Homo sapiens 119594378
4758356
P39748
Fpg formamidopyrimidine-DNA glycosylase [Escherichia coli]. Escherichia coli 146545
P05523
GPS1 COP9 signalosome complex subunit 1, JAB1-containing signalosome subunit 1, G protein pathway suppressor 1, Protein MFH., Homo sapiens 20981690
Q13098
GTF2H1 General transcription factor IIH subunit 1, General transcription factor IIH polypeptide 1, TFIIH basal transcription factor complex p62 subunit, Basic transcription factor 2 62 kDa subunit, Homo sapiens 416727
4885365
P32780
GTF2H2 General transcription factor IIH subunit 2, General transcription factor IIH polypeptide 2, TFIIH basal transcription factor complex p44 subunit, Basic transcription factor 2 44 kDa subunit, Homo sapiens 17380326
6681762
Q13888
GTF2H3 General transcription factor IIH subunit 3, General transcription factor IIH polypeptide 3, TFIIH basal transcription factor complex p34 subunit, Basic transcription factor 2 34 kDa subunit, Homo sapiens 50403772
19923732
Q13889
GTF2H4 General transcription factor IIH subunit 4, General transcription factor IIH polypeptide 4, TFIIH basal transcription factor complex p52 subunit, Basic transcription factor 2 52 kDa subunit, Homo sapiens 17380328
4504201
Q92759
GTF2H5 General transcription factor IIH subunit 5, General transcription factor IIH polypeptide 5, TFIIH basal transcription factor complex TTD-A subunit, TFB5 ortholog., Homo sapiens 67462047
46359855
Q6ZYL4
HUS1 checkpoint protein HUS1 [Homo sapiens]. Homo sapiens 4758576
O60921
HelD helicase IV [Escherichia coli]. Escherichia coli 146328
P15038
Hnt3p DNA 5' AMP hydrolase involved in DNA repair; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins; homolog of Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia Saccharomyces cerevisiae 6324832
Q08702
HolA DNA polymerase III delta subunit [Escherichia coli]. Escherichia coli 145729
P28630
HolB DNA polymerase III delta prime subunit [Escherichia coli]. Escherichia coli 145799
P28631
HolC DNA polymerase III chi subunit [Escherichia coli]. Escherichia coli 145537
P28905
HolD DNA polymerase III psi subunit [Escherichia coli]. Escherichia coli 147387
P28632
HolE DNA polymerase III theta subunit [Escherichia coli]. Escherichia coli 145787
P0ABS8
Kin28p Saccharomyces cerevisiae 6320095
P06242
Ku70 (XRCC6) X-ray repair cross-complementing protein 6, 5'-deoxyribose-5-phosphate lyase Ku70, X-ray repair complementing defective repair in Chinese hamster cells 6, ATP-dependent DNA helicase 2 subunit1, ATP-dependent DNA helicase II 70kDa subunit, Lupus Ku autoantigen protein p70, 70kDa subunit of Ku antigen, Thyroid-lupus autoantigen, CTC box-binding factor 75 kDa subunit, DNA repair protein XRCC6 Homo sapiens 125729
4503841
P12956
Ku80 (XRCC5) X-ray repair cross-complementing protein 5, X-ray repair complementing defective repair in Chinese hamster cells 5, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, Lupus Ku autoantigen protein p86, 86 kDa subunit of Ku antigen, Ku86, Ku80, Thyroid-lupus autoantigen, CTC box-binding factor 85 kDa subunit, Nuclear factor IV, DNA repair protein XRCC5 Homo sapiens 125731
10863945
P13010
LIG1 DNA ligase 1, DNA ligase I, Polydeoxyribonucleotide synthase [ATP] 1., Homo sapiens 118773
4557719
P18858
LIG3 DNA ligase III [Homo sapiens]. Homo sapiens 860963
73747829
Q6UXM1
LIG4 DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4., Homo sapiens 88911290
23199993
148539894
P49917
LexA LexA repressor. Escherichia coli 67467382
P0A7C3
Lif1p Component of the DNA ligase IV complex that mediates nonhomologous end joining in DNA double-strand break repair; physically interacts with Dnl4p and Nej1p; homologous to mammalian XRCC4 protein (LIF1) Saccharomyces cerevisiae 296144956
P53150
MBD4 Methyl-CpG-binding domain protein 4, Methyl-CpG-binding protein MBD4, Methyl-CpG-binding endonuclease 1, Mismatch-specific DNA N-glycosylase., Homo sapiens 50400819
4505121
O95243
MDC1 mediator of DNA damage checkpoint protein 1 [Homo sapiens]. Homo sapiens 132626688
Q14676
MGMT Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase., Homo sapiens 127069
4505177
51247522
P16455
MLH1 DNA mismatch repair protein Mlh1 isoform 1 [Homo sapiens]. Homo sapiens 4557757
P40692
MLH3 DNA mismatch repair protein Mlh3 isoform 2 [Homo sapiens]. Homo sapiens 91992160
Q9UHC1
MMS19 MMS19 nucleotide excision repair protein homolog [Homo sapiens]. Homo sapiens 170763479
Q96T76
MNAT1 CDK-activating kinase assembly factor MAT1 isoform 1 [Homo sapiens]. Homo sapiens 4505225
P51948
MPG DNA-3-methyladenine glycosylase (3-methyladenine DNA glycosidase) (ADPG) (3-alkyladenine DNA glycosylase) (N-methylpurine-DNA glycosylase). Homo sapiens 3915598
62632769
62632771
P29372
MRE11A double-strand break repair protein MRE11A isoform 2 [Homo sapiens]. Homo sapiens 24234690
P49959
MSH2 DNA mismatch repair protein Msh2 [Homo sapiens]. Homo sapiens 4557761
P43246
MSH3 mutS homolog 3 [Homo sapiens]. Homo sapiens 68303635
P20585
MSH4 mutS protein homolog 4 [Homo sapiens]. Homo sapiens 36949366
O15457
MSH5 mutS protein homolog 5 isoform c [Homo sapiens]. Homo sapiens 4505253
O43196
MSH6 DNA mismatch repair protein Msh6 [Homo sapiens]. Homo sapiens 4504191
P52701
MUS81 crossover junction endonuclease MUS81 [Homo sapiens]. Homo sapiens 156151413
Q96NY9
MUTYH A/G-specific adenine DNA glycosylase isoform 1 [Homo sapiens]. Homo sapiens 6912520
48428272
56205990
Q9UIF7
Mag1p 3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired Saccharomyces cerevisiae 6320990
P22134
Mec1p Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for cell cycle arrest and transcriptional responses prompted by damaged or unreplicated DNA; monitors and participates in meiotic recombination Saccharomyces cerevisiae 6319612
P38111
Met18p DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance Saccharomyces cerevisiae 6322063
P40469
Mfd transcription-repair coupling factor [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 1787357
P30958
Mgt1p Saccharomyces cerevisiae 1431330
P26188
Mlh1p Saccharomyces cerevisiae 6323819
P38920
Mlh3p Saccharomyces cerevisiae 6325093
Q12083
Mms2p Saccharomyces cerevisiae 6321351
P53152
Mph1p Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, binds to flap DNA and stimulates activity of Rad27p and Dna2p; mutations confer a mutator phenotype Saccharomyces cerevisiae 6322192
P40562
Mre11p Saccharomyces cerevisiae 1513065
6323880
P32829
Msh2p Saccharomyces cerevisiae 6324482
P25847
Msh3p Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability Saccharomyces cerevisiae 157285763
P25336
Msh4p Saccharomyces cerevisiae 14318519
P40965
Msh5p Saccharomyces cerevisiae 6320047
Q12175
Msh6p Saccharomyces cerevisiae 6320302
Q03834
Mug G/U mismatch-specific DNA glycosylase [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 1789449
P0A9H1
Mus81p Crossover junction endonuclease MUS81, MMS and UV-sensitive protein 81 Saccharomyces cerevisiae 46396280
Q04149
MutH DNA mismatch repair protein mutH, Methyl-directed mismatch repair protein., Escherichia coli 730086
42065
P06722
MutL MutL Protein [Escherichia coli]. Escherichia coli 42067
P23367
MutS MutS [Escherichia coli]. Escherichia coli 17017340
P23909
MutY adenine DNA glycosylase [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16130862
P17802
NBN (NBS1) nibrin, p95 PROTEIN OF THE MRE11/RAD50 COMPLEX Homo sapiens 33356172
67189945
O60934
NEIL1 Endonuclease VIII-like 1, DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Nei-like protein 1, Nei homolog 1, FPG1., Homo sapiens 56404654
13375817
Q96FI4
NEIL2 Endonuclease VIII-like 2, DNA glycosylase/AP lyase Neil2, DNA-(apurinic or apyrimidinic site) lyase Neil2, Nei-like protein 2, Nei homolog 2 Homo sapiens 56404653
21450800
Q969S2
NEIL3 endonuclease VIII-like 3 [Homo sapiens]. Homo sapiens 157388969
Q8TAT5
NHEJ1 Cernunnos protein, XRCC4-like factor, Non-homologous end-joining factor 1 Homo sapiens 85857243
Q9H9Q4
NTH endonuclease III-like protein 1 [Homo sapiens]. Homo sapiens 4505471
29840795
P78549
Nei 5-formyluracil/5-hydroxymethyluracil DNA glycosylase [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16128689
P50465
Nej1p Saccharomyces cerevisiae 296146799
Q06148
Nfo endonuclease IV with intrinsic 3'-5' exonuclease activity [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16130097
P0A6C1
Ntg1p DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair; acts in both nucleus and mitochondrion; creates a double-strand break at mtDNA origins that stimulates replication in response to oxidative stress Saccharomyces cerevisiae 6319304
P31378
Ntg2p DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus; sumoylated Saccharomyces cerevisiae 6324530
Q08214
Nth DNA glycosylase and apyrimidinic (AP) lyase (endonuclease III) [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16129591
P0AB83
OGG1 N-glycosylase/DNA lyase, Includes: 8-oxoguanine DNA glycosylase, Includes: DNA-(apurinic or apyrimidinic site) lyase Homo sapiens 12643548
O15527
Ogg1p Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA, contributes to UVA resistance Saccharomyces cerevisiae 6323580
P53397
Ogt 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase., Methylated-DNA-protein-cysteine methyltransferase, Escherichia coli 84027827
16129296
P0AFH0
PARP1 poly [ADP-ribose] polymerase 1 [Homo sapiens]. Homo sapiens 156523968
P09874
PARP2 poly [ADP-ribose] polymerase 2 isoform 1 [Homo sapiens]. Homo sapiens 110825961
110825963
Q9UGN5
PCNA Proliferating cell nuclear antigen, Cyclin Homo sapiens 129694
4505641
P12004
PMS1 PMS1 protein homolog 1 isoform a [Homo sapiens]. Homo sapiens 4505911
P54277
PMS2 mismatch repair endonuclease PMS2 isoform a [Homo sapiens] Homo sapiens 4505913
P54278
PMS6 PMS6 [Homo sapiens]. Homo sapiens 1304123
Q16544
PNKP bifunctional polynucleotide phosphatase/kinase [Homo sapiens]. Homo sapiens 31543419
Q96T60
POLB DNA polymerase beta [Homo sapiens]. Homo sapiens 4505931
P06746
POLD1 DNA polymerase delta catalytic subunit, DNA polymerase subunit delta p125 Homo sapiens 50403732
156616275
P28340
POLDIP2 Polymerase delta-interacting protein 2, 38 kDa DNA polymerase delta interaction protein, Homo sapiens 50401206
Q9Y2S7
POLDIP3 Polymerase delta-interacting protein 3, 46 kDa DNA polymerase delta interaction protein, S6K1 Aly/REF-like target, Homo sapiens 50403796
Q9BY77
POLE DNA polymerase epsilon catalytic subunit A [Homo sapiens]. Homo sapiens 62198237
116241339
Q07864
POLE2 DNA polymerase epsilon subunit 2, DNA polymerase II subunit 2, DNA polymerase epsilon subunit B., Homo sapiens 3915676
P56282
POLE3 DNA polymerase epsilon subunit 3, DNA polymerase II subunit 3, DNA polymerase epsilon subunit p17, Chromatin accessibility complex 17 kDa protein, Arsenic-transactivated protein, Homo sapiens 22653710
Q9NRF9
POLE4 DNA polymerase epsilon subunit 4, DNA polymerase epsilon subunit p12, DNA polymerase II subunit 4., Homo sapiens 116241340
Q9NR33
POLG DNA polymerase subunit gamma-1 [Homo sapiens]. Homo sapiens 4505937
187171277
P54098
POLH DNA polymerase eta [Homo sapiens]. Homo sapiens 5729982
Q9Y253
POLI DNA polymerase iota [Homo sapiens]. Homo sapiens 154350220
Q9UNA4
POLK DNA polymerase kappa [Homo sapiens]. Homo sapiens 7705344
Q9UBT6
POLL DNA polymerase lambda, DNA polymerase beta-2, Homo sapiens 17367126
7019491
Q9UGP5
POLM DNA polymerase mu, Homo sapiens 17366980
7019493
Q9NP87
POLN DNA polymerase nu [Homo sapiens]. Homo sapiens 112420958
Q7Z5Q5
POLQ DNA polymerase theta isoform 1 [Homo sapiens]. Homo sapiens 40805845
O75417
POLR2E DNA-directed RNA polymerases I, II, and III subunit RPABC1, DNA-directed RNA polymerase II subunit E, RPB5 homolog, DNA-directed RNA polymerase II 23 kDa polypeptide, XAP4., Homo sapiens 116242767
P19388
POLR2F DNA-directed RNA polymerases I, II, and III subunit RPABC2, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide, RPABC14.4, RPB6 homolog, RPC15., Homo sapiens 47117761
P61218
POLR2H DNA-directed RNA polymerases I, II, and III subunit RPABC3, DNA-directed RNA polymerase II subunit H, DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide, RPB17, RPB8 homolog, Homo sapiens 20178325
P52434
POLR2K DNA-directed RNA polymerases I, II, and III subunit RPABC4, DNA-directed RNA polymerase II subunit K, RPB10alpha, RNA polymerase II 7.0 kDa subunit, ABC10-alpha., Homo sapiens 1710664
P53803
POLR2L DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerase III subunit L, RPB10 homolog, RNA polymerase II 7.6 kDa subunit, Homo sapiens 51338657
P62875
PRKDC DNA-dependent protein kinase catalytic subunit, DNPK1, p460., Homo sapiens 38258929
9188646
13654237
P78527
Phr CPD photolyase, DNA photolyase Escherichia coli 6006450
P00914
Phr1p CPD photolyase, DNA photolyase Saccharomyces cerevisiae 1420831
P05066
Pms1p ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL Saccharomyces cerevisiae 46562124
P14242
Pol delta DNA polymerase III, Hys2p, Pol31p Saccharomyces cerevisiae 1256943
P46957
Pol epsilon Catalytic subunit of DNA polymerase (II) epsilon, a chromosomal DNA replication polymerase that exhibits processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair; interacts extensively with Mrc1p Saccharomyces cerevisiae 6324067
1045247
P21951
Pol30p PCNA Saccharomyces cerevisiae 6319564
P15873
Pol32p Saccharomyces cerevisiae 6322503
P47110
Pol3p Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER) Saccharomyces cerevisiae 6320101
1199547
P15436
Pol4p DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta Saccharomyces cerevisiae 10383782
P25615
PolI DNA polymerase I [Escherichia coli] Escherichia coli 147312
42461
P00582
PolII DNA polymerase II [Escherichia coli]. Escherichia coli 147318
P21189
Pso2p Nuclease required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation Saccharomyces cerevisiae 6323786
P30620
RAD1 cell cycle checkpoint protein RAD1 [Homo sapiens]. Homo sapiens 4506385
O60671
RAD17 cell cycle checkpoint protein RAD17 isoform 1 [Homo sapiens]. Homo sapiens 4506383
O75943
RAD18 postreplication repair protein hRAD18p [Homo sapiens]. Homo sapiens 14550405
Q9NS91
RAD23A UV excision repair protein RAD23 homolog A [Homo sapiens]. Homo sapiens 4826964
P54725
RAD23B UV excision repair protein RAD23 homolog B [Homo sapiens]. Homo sapiens 4506387
P54727
RAD50 DNA repair protein RAD50 [Homo sapiens]. Homo sapiens 19924129
Q92878
RAD51 DNA repair protein RAD51 homolog 1 isoform 1 [Homo sapiens]. Homo sapiens 19924133
Q06609
RAD51C DNA repair protein RAD51 homolog 3 isoform 2 [Homo sapiens]. Homo sapiens 4506391
O43502
RAD51L1 DNA repair protein RAD51 homolog 2 isoform 1 [Homo sapiens]. Homo sapiens 10835029
19924117
O15315
RAD51L3 RAD51-like 3 isoform 1 [Homo sapiens]. Homo sapiens 19924119
O75771
RAD52 RAD52 homolog isoform alpha [Homo sapiens]. Homo sapiens 20143952
P43351
RAD54B DNA repair and recombination protein RAD54B [Homo sapiens]. Homo sapiens 6912622
Q9Y620
RAD54L RAD54-like protein [Homo sapiens]. Homo sapiens 4506397
Q92698
RAD9A cell cycle checkpoint control protein RAD9A [Homo sapiens]. Homo sapiens 4759022
Q99638
RBBP8 retinoblastoma-binding protein 8 isoform a [Homo sapiens]. Homo sapiens 4506441
Q99708
RECQL ATP-dependent DNA helicase Q1 [Homo sapiens]. Homo sapiens 14591904
P46063
RECQL2 (WRN) Werner syndrome ATP-dependent helicase [Homo sapiens]. Homo sapiens 110735439
Q14191
RECQL4 RecQ protein-like 4 [Homo sapiens]. Homo sapiens 116812616
O94761
RECQL5 ATP-dependent DNA helicase Q5 isoform 2 [Homo sapiens]. Homo sapiens 51242947
O94762
REV1 DNA repair protein REV1 isoform 1 [Homo sapiens]. Homo sapiens 7706681
Q9UBZ9
REV3L DNA polymerase zeta catalytic subunit [Homo sapiens]. Homo sapiens 153792012
O60673
RFC1 Replication factor C subunit 1, Activator 1 subunit 1, Replication factor C large subunit, Replication factor C 140 kDa subunit, Activator 1 140 kDa subunit, Activator 1 large subunit, DNA-binding protein PO-GA., Homo sapiens 56757608
30353858
P35251
RFC2 Replication factor C subunit 2, Activator 1 subunit 2, Replication factor C 40 kDa subunit, Activator 1 40 kDa subunit, Homo sapiens 2507300
P35250
RFC3 Replication factor C subunit 3, Activator 1 subunit 3, Replication factor C 38 kDa subunit, Activator 1 38 kDa subunit, Homo sapiens 3915601
P40938
RFC4 Replication factor C subunit 4, Activator 1 subunit 4, Replication factor C 37 kDa subunit, Activator 1 37 kDa subunit, Homo sapiens 1703052
P35249
RFC5 Replication factor C subunit 5, Activator 1 subunit 5, Replication factor C 36 kDa subunit, Activator 1 36 kDa subunit, Homo sapiens 728777
P40937
RPA1 Replication protein A 70 kDa DNA-binding subunit, Replication factor A protein 1, Single-stranded DNA-binding protein., Homo sapiens 1350579
4506583
P27694
RPA2 Replication protein A 32 kDa subunit, Replication protein A 34 kDa subunit, Replication factor A protein 2, Homo sapiens 132474
4506585
P15927
RPA3 Replication protein A 14 kDa subunit, Replication factor A protein 3, Homo sapiens 464608
4506587
P35244
RRM2B ribonucleoside-diphosphate reductase subunit M2 B isoform 1 [Homo sapiens]. Homo sapiens 42544136
Q7LG56
Rad10p Saccharomyces cerevisiae 6323543
P06838
Rad14p Protein that recognizes and binds damaged DNA during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); contains zinc finger motif; homolog of human XPA protein Saccharomyces cerevisiae 6323857
P28519
Rad18p E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair Saccharomyces cerevisiae 6319911
P10862
Rad1p Saccharomyces cerevisiae 6325235
P06777
Rad23p Protein with ubiquitin-like N terminus, subunit of Nuclear Excision Repair Factor 2 (NEF2) with Rad4p that recognizes and binds damaged DNA; enhances protein deglycosylation activity of Png1p; homolog of human HR23A and HR23B Saccharomyces cerevisiae 6320798
P32628
Rad26p Protein involved in transcription-coupled nucleotide excision repair of UV-induced DNA lesions; recruitment to DNA lesions is dependent on an elongating RNA polymerase II; homolog of human CSB protein (RAD26) Saccharomyces cerevisiae 296146044
P40352
Rad27p 5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family Saccharomyces cerevisiae 6322736
P26793
Rad28p Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair Saccharomyces cerevisiae 6320233
Q12021
Rad2p Saccharomyces cerevisiae 6321697
P07276
Rad30p DNA polymerase eta, involved in tranlesion synthesis during post-replication repair; catalyzes the synthesis of DNA opposite cyclobutane pyrimidine dimers and other lesions; mutations in human pol eta are responsible for XPV Saccharomyces cerevisiae 6320627
Q04049
Rad3p 5' to 3' DNA helicase, involved in nucleotide excision repair and transcription; subunit of RNA polymerase II transcription initiation factor TFIIH; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein Saccharomyces cerevisiae 6321019
P06839
Rad4p Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein Saccharomyces cerevisiae 6321010
P14736
Rad50p Saccharomyces cerevisiae 1255968
P12753
Rad51p Saccharomyces cerevisiae 4275
6320942
P25454
Rad52p Saccharomyces cerevisiae 575687
P06778
Rad54p Saccharomyces cerevisiae 728692
P32863
Rad57p Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad55p Saccharomyces cerevisiae 6320207
P25301
RecA RecA [Escherichia coli]. Escherichia coli 37362719
P0A7G6
RecB exonuclease V (RecBCD complex), beta subunit [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16130724
P08394
RecC exonuclease V (RecBCD complex), gamma chain [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16130726
P07648
RecD exonuclease V (RecBCD complex), alpha chain [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16130723
P04993
RecE recE [Escherichia coli]. Escherichia coli 147536
P15032
RecF RecF [Escherichia coli]. Escherichia coli 147539
P0A7H0
RecG recG [Escherichia coli]. Escherichia coli 42669
P24230
RecJ single-stranded DNA-specific exonuclease [Escherichia coli]. Escherichia coli 887842
P21893
RecN unnamed protein product [Escherichia coli]. Escherichia coli 42693
P05824
RecO recO [Escherichia coli]. Escherichia coli 499369
P0A7H3
RecQ recQ [Escherichia coli]. Escherichia coli 147559
P15043
RecR gap repair protein [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16128456
P0A7H6
RecT unknown [Escherichia coli]. Escherichia coli 397681
P33228
Rev3p Catalytic subunit of DNA polymerase zeta, involved in translesion synthesis during post-replication repair; required for mutagenesis induced by DNA damage; involved in double-strand break repair Saccharomyces cerevisiae 6325090
P14284
Rfc5p Saccharomyces cerevisiae 296142756
P38251
Rnr4p Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits Saccharomyces cerevisiae 6321619
P49723
Rpa1p Saccharomyces cerevisiae 88191850
P10964
RuvA unnamed protein product [Escherichia coli]. Escherichia coli 581226
P0A809
RuvB unnamed protein product [Escherichia coli]. Escherichia coli 42903
P0A812
RuvC ruvC [Escherichia coli]. Escherichia coli 42175
P0A814
SHFM1 26S proteasome complex subunit DSS1 [Homo sapiens]. Homo sapiens 5453640
P60896
SMUG1 single-strand selective monofunctional uracil DNA glycosylase [Homo sapiens]. Homo sapiens 7657597
Q53HV7
SbcC unnamed protein product [Escherichia coli]. Escherichia coli 42914
P13458
Sem1p Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; involved in mRNA export mediated by the TREX-2 complex (Sac3p-Thp1p); ortholog of human DSS1 Saccharomyces cerevisiae 6320571
O94742
Sgs1p Nucleolar DNA helicase of the RecQ family involved in genome integrity maintenance; regulates chromosome synapsis and meiotic joint molecule/crossover formation; similar to human BLM and WRN proteins implicated in Bloom and Werner syndromes Saccharomyces cerevisiae 6323844
P35187
Spo11p Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation Saccharomyces cerevisiae 6321765
P23179
Ssb single-stranded DNA-binding protein [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16131885
P0AGE0
Ssl1p Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kinase and DNA-dependent ATPase/helicase activities and is essential for transcription and nucleotide excision repair; interacts with Tfb4p Saccharomyces cerevisiae 6323033
Q04673
Ssl2p Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3 Saccharomyces cerevisiae 6322048
Q00578
SulA SOS cell division inhibitor [Escherichia coli str. K-12 substr. W3110]. Escherichia coli 89107808
P0AFZ5
TDG G/T mismatch-specific thymine DNA glycosylase, Thymine-DNA glycosylase Homo sapiens 46397791
59853162
Q13569
TDP1 Tyrosyl-DNA phosphodiesterase 1, Homo sapiens 37999797
20127586
57242805
Q9NUW8
TFB1 Subunit of TFIIH and nucleotide excision repair factor 3 complexes, required for nucleotide excision repair, target for transcriptional activators Saccharomyces cerevisiae 6320517
P32776
TOPBP1 DNA topoisomerase 2-binding protein 1, DNA topoisomerase II-beta-binding protein 1 Homo sapiens Q92547
TP53 cellular tumor antigen p53 isoform a [Homo sapiens]. Homo sapiens 120407068
P04637
TREX1 three prime repair exonuclease 1 isoform b [Homo sapiens]. Homo sapiens 18375535
Q9NSU2
TREX2 three prime repair exonuclease 2 isoform a; expressed-Xq28STS protein; 26S proteasome-associated UCH interacting protein 1; 3'-5' exonuclease; Xq28, 2000bp sequence contg. ORF [Homo sapiens]. Homo sapiens 6005918
Q9BQ50
Tag 3-methyl-adenine DNA glycosylase I, constitutive [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16131420
P05100
Tdp1p Saccharomyces cerevisiae 6319701
P38319
Tel1p Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene Saccharomyces cerevisiae 6319383
P38110
Tfb2p Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair, similar to 52 kDa subunit of human TFIIH Saccharomyces cerevisiae 6325135
Q02939
Tfb3p Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit Saccharomyces cerevisiae 6320668
Q03290
Tfb4p Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p Saccharomyces cerevisiae 6325313
Q12004
Tfb5p Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair Saccharomyces cerevisiae 13129164
Q3E7C1
Topoisomerase I (sub omega) unnamed protein product [Escherichia coli]. Escherichia coli 415338
P06612
UNG Uracil-DNA glycosylase, Homo sapiens 37999897
19718751
P13051
Ubc13p Saccharomyces cerevisiae 6320297
P52490
UmuC UmuC [Escherichia coli]. Escherichia coli 84060801
P04152
UmuD UmuD [Escherichia coli]. Escherichia coli 85376582
P0AG11
Ung uracil DNA glycosylase [Escherichia coli]. Escherichia coli 148149
P12295
Ung1p Saccharomyces cerevisiae 6323620
P12887
UvrA ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16131884
P0A698
UvrB UvrABC system protein B, Excinuclease ABC subunit B., Escherichia coli 67474768
P0A8F8
UvrC UvrABC system protein C, Excinuclease ABC subunit C., Escherichia coli 189038049
A1AC65
UvrD DNA helicase II [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 148212
P03018
XPA DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein., Homo sapiens 139816
4507937
P23025
XPB TFIIH basal transcription factor complex helicase XPB subunit, Basic transcription factor 2 89 kDa subunit, TFIIH basal transcription factor complex 89 kDa subunit, DNA repair protein complementing XP-B cells, Xeroderma pigmentosum group B-complementing protein, DNA excision repair protein ERCC-3., Homo sapiens 119541
4557563
P19447
XPC xeroderma pigmentosum, complementation group C [Homo sapiens]. Homo sapiens 20127460
Q01831
XPD TFIIH basal transcription factor complex helicase subunit, Basic transcription factor 2 80 kDa subunit, TFIIH basal transcription factor complex 80 kDa subunit, DNA repair protein complementing XP-D cells, Xeroderma pigmentosum group D-complementing protein, CXPD, DNA excision repair protein ERCC-2., Homo sapiens 119540
15834617
P18074
XPF DNA repair endonuclease XPF, DNA excision repair protein ERCC-4, DNA repair protein complementing XP-F cells, Xeroderma pigmentosum group F-complementing protein., Homo sapiens 2842712
4885217
Q92889
XPG DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5). Homo sapiens 160332328
51988900
267420
P28715
XRCC1 DNA repair protein XRCC1, X-ray repair cross-complementing protein 1 Homo sapiens 190684675
P18887
XRCC2 DNA repair protein XRCC2, X-ray repair cross-complementing protein 2 Homo sapiens 4885657
O43543
XRCC3 DNA repair protein XRCC3, X-ray repair cross-complementing protein 3 Homo sapiens 4885659
153946427
O43542
XRCC4 DNA repair protein XRCC4, X-ray repair cross-complementing protein 4., Homo sapiens 44888352
4507945
Q13426
XprB xprB [Escherichia coli]. Escherichia coli 147548
P0A8P8
Xrs2p Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling (XRS2) Saccharomyces cerevisiae 296143718
P33301
XseA exonuclease VII large subunit [Escherichia coli]. Escherichia coli 148275
P04994
XseB exonuclease VII small subunit [Escherichia coli str. K-12 substr. W3110]. Escherichia coli 89107292
P0A8G9
XthA exonuclease III [Escherichia coli str. K-12 substr. MG1655]. Escherichia coli 16129703
P09030
Yku70p Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair Saccharomyces cerevisiae 6323940
P32807
Yku80p Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair (YKU80) Saccharomyces cerevisiae 296147223
Q04437
albumin
catalase W5S153_9LAMI
test vxcvxcvc Saccharomyces cerevisiae cxvcxvcx

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